Cognitive Impairment in Bipolar Disorder: Treatment and Prevention Strategies.

Cognitive Impairment in Bipolar Disorder: Treatment and Prevention Strategies.
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躁郁症的认知障碍:治疗和预防策略。

DOI:
10.1093/ijnp/pyx032
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发表时间:
2017-08-01
期刊:
The international journal of neuropsychopharmacology
影响因子:
--
通讯作者:
Vieta E
Vieta E
中科院分区:
其他
文献类型:
--
作者:
Solé B;Jiménez E;Torrent C;Reinares M;Bonnin CDM;Torres I;Varo C;Grande I;Valls E;Salagre E;Sanchez-Moreno J;Martinez-Aran A;Carvalho AF;Vieta E

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在过去的十年中,人们越来越认识到识别和治疗双相情感障碍相关的认知障碍的重要性,因为它持续存在于缓解期。有证据表明,神经认知功能障碍可能显著影响患者的社会心理结局。越来越多的研究试图更好地了解双相情感障碍认知障碍的潜在调节因素,以便制定预防策略和有效治疗。本综述从药理学和心理学的角度对双相情感障碍认知功能障碍的治疗方法以及潜在的新治疗方法的现有研究数据进行了概述。所有这些数据都鼓励了进一步研究的发展,以找到预防和治疗双相情感障碍相关认知障碍的有效策略。这些努力可能最终导致这些患者的社会心理功能的改善。
Over the last decade, there has been a growing appreciation of the importance of identifying and treating cognitive impairment associated with bipolar disorder, since it persists in remission periods. Evidence indicates that neurocognitive dysfunction may significantly influence patients’ psychosocial outcomes. An ever-increasing body of research seeks to achieve a better understanding of potential moderators contributing to cognitive impairment in bipolar disorder in order to develop prevention strategies and effective treatments. This review provides an overview of the available data from studies examining treatments for cognitive dysfunction in bipolar disorder as well as potential novel treatments, from both pharmacological and psychological perspectives. All these data encourage the development of further studies to find effective strategies to prevent and treat cognitive impairment associated with bipolar disorder. These efforts may ultimately lead to an improvement of psychosocial functioning in these patients.
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