Factors Affecting COVID-19 Vaccine Acceptance: An International Survey among Low- and Middle-Income Countries.

Factors Affecting COVID-19 Vaccine Acceptance: An International Survey among Low- and Middle-Income Countries.
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DOI:
10.3390/vaccines9050515
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发表时间:
2021-05-17
期刊:
影响因子:
7.8
通讯作者:
Colebunders R
Colebunders R
中科院分区:
医学3区
文献类型:
--
作者:
Bono SA;Faria de Moura Villela E;Siau CS;Chen WS;Pengpid S;Hasan MT;Sessou P;Ditekemena JD;Amodan BO;Hosseinipour MC;Dolo H;Siewe Fodjo JN;Low WY;Colebunders R

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疫苗接种正迅速成为应对当前 COVID-19 大流行的关键干预措施。我们进行了横断面在线调查,以调查 9 个低收入和中等收入国家 (LMIC;N = 10,183) 对 COVID-19 疫苗的接受情况,假设疫苗有效性为 90% 和 95%。疫苗接受率从 76.4%(90% 有效性)增加到 88.8%(95% 有效性)。考虑到疫苗的有效率为 90%,马来西亚、泰国、孟加拉国和五个非洲国家(刚果民主共和国、贝宁、乌干达、马拉维和马里)的接受率低于巴西。认为接种疫苗对保护自己很重要的个人的接受几率最高 (aOR 2.49),有效率达 95%。疫苗接受度也与 COVID-19 知识、对 COVID-19 的担忧/恐惧、较高收入、较年轻和 COVID-19 检测呈阴性呈正相关。然而,慢性病和女性降低了接受疫苗的几率。拒绝接种疫苗的主要原因是担心副作用(41.2%)和对疫苗有效性缺乏信心(15.1%)。需要进一步研究来确定各国对疫苗犹豫不决的具体原因,以便制定缓解策略,确保中低收入国家的高且公平的疫苗接种覆盖率。
Vaccination is fast becoming a key intervention against the ongoing COVID-19 pandemic. We conducted cross-sectional online surveys to investigate COVID-19 vaccine acceptance across nine Low- and Middle-Income Countries (LMICs; N = 10,183), assuming vaccine effectiveness at 90% and 95%. The prevalence of vaccine acceptance increased from 76.4% (90% effectiveness) to 88.8% (95% effectiveness). Considering a 90% effective vaccine, Malaysia, Thailand, Bangladesh, and five African countries (Democratic Republic of Congo, Benin, Uganda, Malawi, and Mali) had lower acceptance odds compared to Brazil. Individuals who perceived taking the vaccine as important to protect themselves had the highest acceptance odds (aOR 2.49) at 95% effectiveness.Vaccine acceptance was also positively associated with COVID-19 knowledge, worry/fear regarding COVID-19, higher income, younger age, and testing negative for COVID-19. However, chronic disease and female gender reduced the odds for vaccine acceptance. The main reasons underpinning vaccine refusal were fear of side effects (41.2%) and lack of confidence in vaccine effectiveness (15.1%). Further research is needed to identify country-specific reasons for vaccine hesitancy in order to develop mitigation strategies that would ensure high and equitable vaccination coverage across LMICs.
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