Outer hair cell driven reticular lamina mechanical distortion in living cochleae.
Outer hair cell driven reticular lamina mechanical distortion in living cochleae.
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DOI：
10.1016/j.heares.2021.108405
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发表时间：
2022-09-15
期刊：
影响因子：
2.8
通讯作者：
Nuttall AL
中科院分区：
文献类型：
--
作者：
Burwood G;He WX;Fridberger A;Ren TY;Nuttall AL
耳蜗畸变为研究人员和临床医生提供了内耳信号处理机制的条件和特性的一瞥。直到最近，我们对这些失真的检查仅限于测量基底膜的振动或记录耳道中的声失真输出。尽管其重要性，耳蜗畸变的产生机制仍然是一个实质性的任务，以了解。在啮齿动物模型中测量网状椎板振动的能力是最近的实验进展。令人惊讶的力学特性已经被揭示出来。这些特性值得在我们目前对扭曲的理解的背景下进行讨论，并评估耳蜗力学新解释的意义。这篇综述集中在我们研究小组最近的一些数据上，并讨论了这些数据对我们理解外围发声加工的意义，以及它们对未来实验方向的影响。
Cochlear distortions afford researchers and clinicians a glimpse into the conditions and properties of inner ear signal processing mechanisms. Until recently, our examination of these distortions has been limited to measuring the vibration of the basilar membrane or recording acoustic distortion output in the ear canal. Despite its importance, the generation mechanism of cochlear distortion remains a substantial task to understand. The ability to measure the vibration of the reticular lamina in rodent models is a recent experimental advance. Surprising mechanical properties have been revealed. These properties merit both discussion in context with our current understanding of distortion, and appraisal of the significance of new interpretations of cochlear mechanics. This review focusses on some of the recent data from our research groups and discusses the implications of these data on our understanding of vocalization processing in the periphery, and their influence upon future experimental directions.
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通讯作者：
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