Development of polyacrylic acid-functionalized porous zinc sulfide nanospheres for a non-aqueous solid phase extraction procedure toward alkaloids
Development of polyacrylic acid-functionalized porous zinc sulfide nanospheres for a non-aqueous solid phase extraction procedure toward alkaloids
复制标题
开发聚丙烯酸功能化多孔硫化锌纳米球用于生物碱的非水固相萃取程序
DOI：
10.1039/c5ra02827b
复制
发表时间：
2015-03
期刊：
影响因子：
3.9
通讯作者：
Gu, Chao-Qian
中科院分区：
文献类型：
--
作者：
Wang, Jun;Zhu, Jun-Min;Ni, Wen-Ting;Gu, Chao-Qian
聚合物基阳离子交换剂和硅胶基吸附剂通常用于生物碱的常规固相萃取，因为它们在固定相和样品之间既提供了离子交换作用，又提供了强烈的疏水作用。然而，较强的疏水相互作用会导致一些非生物碱类化合物的滞留，从而降低生物碱的选择性。以新型聚丙烯酸功能化多孔硫化锌纳米球(PAA-PZN)为吸附剂，建立并优化了一种非水相固相萃取(SPE)方法。通过将聚丙烯酸均聚物与氨基修饰的PZN进行酰胺化反应，得到了富含羧基的SPE吸附剂，有效地去除了非生物碱类化合物，并从萃取物中浓缩了生物碱。它们不仅对生物碱具有高提取效率、高选择性和高回收率，而且具有良好的化学稳定性和机械稳定性。因此，PAA功能化的多孔硫化锌纳米球和随后制备的非水固相萃取(SPE)过程可能被证明是从提取物中选择性浓缩生物碱的有力工具。
A polymer-based cation exchanger and silica-based sorbents are generally used for the conventional solid phase extraction (SPE) toward alkaloids, because they provide both ion exchange interactions and strong hydrophobic interactions between the stationary phase and samples. However, strong hydrophobic interactions could cause the retention of some non-alkaloid compounds, to reduce the selectivity for alkaloids. In this paper, a non-aqueous solid phase extraction (SPE) procedure was developed and optimized utilizing novel polyacrylic acid-functionalized porous zinc sulfide nanospheres (PAA–PZNs) as the sorbents for the enrichment of alkaloids. The SPE sorbents were fabricated by the amidation reaction of the poly-(acrylic acid) homopolymer with amino group modified PZNs, which afforded an abundance of carboxyl groups, to effectively eliminate non-alkaloid compounds and concentrate alkaloids from the extracts. They exhibited not only high extraction efficiency, high selectivity and high recoveries for alkaloids, but also good chemical and mechanical stability. Therefore, the PAA functionalized porous zinc sulfide nanospheres and subsequently prepared non-aqueous solid phase extraction (SPE) procedure may prove to be a strong tool for selective enrichment of alkaloids from extracts.
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DOI：
10.1002/bmc.1292
发表时间：
2009-07
期刊：
Biomedical chromatography : BMC
影响因子：
--
作者：
P. Morgan;V. Manwaring;R. Flanagan
通讯作者：
P. Morgan;V. Manwaring;R. Flanagan
DOI：
10.1039/c3an00003f
发表时间：
2013-04
期刊：
The Analyst
影响因子：
--
作者：
Shuxia Xu;Xinfeng Zhang;Yonghua Sun;D. Yu
通讯作者：
Shuxia Xu;Xinfeng Zhang;Yonghua Sun;D. Yu
影响因子：
3.1
作者：
Elaine Rocha da Luz;Thiago Fernando Mota Gonsalves;R. Aucélio
通讯作者：
Elaine Rocha da Luz;Thiago Fernando Mota Gonsalves;R. Aucélio
DOI：
10.1021/je000175o
发表时间：
2001-01-01
期刊：
JOURNAL OF CHEMICAL AND ENGINEERING DATA
影响因子：
--
作者：
de Lucas, A;Valverde, JL;Rodríguez, JF
通讯作者：
Rodríguez, JF
影响因子：
--
作者：
He-Fang Wang;Yan Li;Ye-Yu Wu;Yu He;Xiu‐Ping Yan
通讯作者：
He-Fang Wang;Yan Li;Ye-Yu Wu;Yu He;Xiu‐Ping Yan