Proteobacteria: A Common Factor in Human Diseases.
Proteobacteria: A Common Factor in Human Diseases.
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DOI:
10.1155/2017/9351507
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发表时间:
2017
影响因子:
--
通讯作者:
Gasbarrini A
中科院分区:
文献类型:
--
作者:
Rizzatti G;Lopetuso LR;Gibiino G;Binda C;Gasbarrini A
Microbiota represents the entire microbial community present in the gut host. It serves several functions establishing a mutualistic relation with the host. Latest years have seen a burst in the number of studies focusing on this topic, in particular on intestinal diseases. In this scenario, Proteobacteria are one of the most abundant phyla, comprising several known human pathogens. This review highlights the latest findings on the role of Proteobacteria not only in intestinal but also in extraintestinal diseases. Indeed, an increasing amount of data identifies Proteobacteria as a possible microbial signature of disease. Several studies demonstrate an increased abundance of members belonging to this phylum in such conditions. Major evidences currently involve metabolic disorders and inflammatory bowel disease. However, more recent studies suggest a role also in lung diseases, such as asthma and chronic obstructive pulmonary disease, but evidences are still scant. Notably, all these conditions are sustained by various degree of inflammation, which thus represents a core aspect of Proteobacteria-related diseases.
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影响因子:
3.7
作者:
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通讯作者:
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影响因子:
7.7
作者:
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通讯作者:
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DOI:
10.1126/science.aam9949
发表时间:
2017-08-11
期刊:
Science (New York, N.Y.)
影响因子:
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作者:
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通讯作者:
Bäumler AJ
DOI:
10.1038/ismej.2012.153
发表时间:
2013-04
期刊:
The ISME journal
影响因子:
--
作者:
通讯作者:
--
影响因子:
8.2
作者:
Brunkwall L;Orho-Melander M
通讯作者:
Orho-Melander M