Dietary Fructose and Fructose-Induced Pathologies.
Dietary Fructose and Fructose-Induced Pathologies.
复制标题
饮食果糖和果糖诱导的病理。
DOI:
10.1146/annurev-nutr-062220-025831
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发表时间:
2022-08-22
影响因子:
8.9
通讯作者:
中科院分区:
文献类型:
--
作者:
The consumption of fructose as sugar and high-fructose corn syrup has markedly increased during the past several decades. This trend coincides with the exponential rise of metabolic diseases, including obesity, nonalcoholic fatty liver disease, cardiovascular disease, and diabetes. While the biochemical pathways of fructose metabolism were elucidated in the early 1990s, organismal-level fructose metabolism and its whole-body pathophysiological impacts have been only recently investigated. In this review, we discuss the history of fructose consumption, biochemical and molecular pathways involved in fructose metabolism in different organs and gut microbiota, the role of fructose in the pathogenesis of metabolic diseases, and the remaining questions to treat such diseases.
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影响因子:
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Cani PD;de Vos WM
通讯作者:
de Vos WM
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10.1080/09637486.2020.1773415
发表时间:
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