Inward collapse of the nasal cavity: Perinatal consolidation of the midface and cranial base in primates

Inward collapse of the nasal cavity: Perinatal consolidation of the midface and cranial base in primates
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鼻腔向内塌陷:灵长类动物中面部和颅底的围产期实变

DOI:
10.1002/ar.24537
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发表时间:
2020
期刊:
The Anatomical Record
影响因子:
--
通讯作者:
DeLeon, Valerie B.
DeLeon, Valerie B.
中科院分区:
--
文献类型:
--
作者:
Smith, Timothy D.;Ufelle, Alexander C.;Cray, James J.;Rehorek, Susan B.;DeLeon, Valerie B.

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由于眶间宽度受到中度到严重的限制,现存的灵长类动物在鼻腔空间和结构方面表现出复杂的减少趋势。在这里,我们描述了灵长类软骨鼻囊后端的个体发育,即环绕嗅区后端的顶针状后鼻杯(PNC)。我们用链状灵长类动物和两种非灵长类动物(Tupaia belangeri,Rousettus leschenaulti)的组织切片标本,以及组织化学和免疫组织化学方法对围产期标本中的PNC进行了研究。在出生时,大多数链状动物只有PNC的片段,而这些片段缺乏软骨膜。几个物种的胎儿标本显示了更完整的PNC,但软骨对II型胶原抗体的反应不均匀或很弱。此外,间隔软骨中的基质相对较少,导致软骨细胞聚集,其中一些细胞与邻近结缔组织直接接触。在一种灵长类动物(Vareciaspp.)和非灵长类动物一样,PNC在出生时就有软骨膜。在年龄较大的婴幼儿Varecia和Rousettus中,PNC的软骨膜缺失,PNC的后极已发生碎裂。PNC软骨膜的丢失似乎先于鼻囊后端的吸收。这些结果表明,与其他哺乳动物相比,灵长类动物的颅底和面部骨骼的巩固发生得更早。我们推测,在蝶筛关节处软骨的早期丢失限制了鼻腔复杂性的软骨机制,如间质扩张或软骨内骨化。
Living primates show a complex trend in reduction of nasal cavity spaces and structures due to moderate to severe constraint on interorbital breadth. Here we describe the ontogeny of the posterior end of the primate cartilaginous nasal capsule, the thimble shaped posterior nasal cupula (PNC), which surrounds the hind end of the olfactory region. We used a histologically sectioned sample of strepsirrhine primates and two non‐primates (Tupaia belangeri,Rousettus leschenaulti), and histochemical and immunohistochemical methods to study the PNC in a perinatal sample. At birth, most strepsirrhines possess only fragments of PNC, and these lack a perichondrium. Fetal specimens of several species reveal a more complete PNC, but the cartilage exhibits uneven or weak reactivity to type II collagen antibodies. Moreover, there is relatively less matrix than in the septal cartilage, resulting in clustering of chondrocytes, some of which are in direct contact with adjacent connective tissues. In one primate (Vareciaspp.) and both non‐primates, the PNC has a perichondrium at birth. In older, infantVareciaandRousettus, the perichondrium of the PNC is absent, and PNC fragmentation at its posterior pole has occurred in the former. Loss of the perichondrium for the PNC appears to precede resorption of the posterior end of the nasal capsule. These results suggest that the consolidation of the basicranial and facial skeletons happens ontogenetically earlier in primates than other mammals. We hypothesize that early loss of cartilage at the sphenoethmoidal articulation limits chondral mechanisms for nasal complexity, such as interstitial expansion or endochondral ossification.
基于组织学、计算机断层扫描和计算流体动力学相结合的方法研究侏儒懒猴 (Nycticebus pygmaeus) 的鼻气流
DOI: --
发表时间: 2019
影响因子: 2.8
作者:
T. Smith;B. Craven;Serena M Engel;C. Bonar;V. DeLeon
通讯作者: V. DeLeon
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DOI: --
发表时间: 2014
影响因子: 2.8
作者:
T. Smith;Ethan S. Kentzel;Jayna M Cunningham;A. Bruening;Kathryn D. Jankord;S. Trupp;C. Bonar;S. Rehorek;V. DeLeon
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