Mechanisms controlling diversification of olfactory sensory neuron classes.

Mechanisms controlling diversification of olfactory sensory neuron classes.
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DOI:
10.1007/s00018-017-2512-2
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发表时间:
2017-09
期刊:
Cellular and molecular life sciences : CMLS
影响因子:
--
通讯作者:
Chuang CF
Chuang CF
中科院分区:
其他
文献类型:
--
作者:
Hsieh YW;Alqadah A;Chuang CF

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动物在恶劣和波动的环境中生存,使用感觉神经元来检测和响应周围环境的变化。嗅觉感觉神经元对于检测食物、识别危险和感知信息素至关重要。感知大量不同类型气味的能力对于区分不同情况至关重要,并且通过嗅觉系统内的神经元多样性来实现。在这里,我们回顾了用于建立嗅觉感觉神经元多样性的各种模式生物,包括C。线虫、果蝇和脊椎动物模型。了解和比较不同动物的神经系统中不同的嗅觉神经元是如何发育的,可以深入了解人类的嗅觉系统是如何形成的。
Animals survive in harsh and fluctuating environments using sensory neurons to detect and respond to changes in their surroundings. Olfactory sensory neurons are essential for detecting food, identifying danger, and sensing pheromones. The ability to sense a large repertoire of different types of odors is crucial to distinguish between different situations, and is achieved through neuronal diversity within the olfactory system. Here, we review the developmental mechanisms used to establish diversity of olfactory sensory neurons in various model organisms, including C. elegans, Drosophila, and vertebrate models. Understanding and comparing how different olfactory neurons develop within the nervous system of different animals can provide insight into how the olfactory system is shaped in humans.
DOI: 10.1016/0092-8674(93)80053-h
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