Mechanisms controlling diversification of olfactory sensory neuron classes.
Mechanisms controlling diversification of olfactory sensory neuron classes.
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DOI:
10.1007/s00018-017-2512-2
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发表时间:
2017-09
期刊:
影响因子:
--
通讯作者:
Chuang CF
中科院分区:
文献类型:
--
作者:
Hsieh YW;Alqadah A;Chuang CF
Animals survive in harsh and fluctuating environments using sensory neurons to detect and respond to changes in their surroundings. Olfactory sensory neurons are essential for detecting food, identifying danger, and sensing pheromones. The ability to sense a large repertoire of different types of odors is crucial to distinguish between different situations, and is achieved through neuronal diversity within the olfactory system. Here, we review the developmental mechanisms used to establish diversity of olfactory sensory neurons in various model organisms, including C. elegans, Drosophila, and vertebrate models. Understanding and comparing how different olfactory neurons develop within the nervous system of different animals can provide insight into how the olfactory system is shaped in humans.
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