Hatched and starved: Two chromatin compaction mechanisms join forces to silence germ cell genome.
Hatched and starved: Two chromatin compaction mechanisms join forces to silence germ cell genome.
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DOI:
10.1083/jcb.202107026
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发表时间:
2021-09-06
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影响因子:
--
通讯作者:
Ercan S
中科院分区:
文献类型:
--
作者:
Morao AK;Ercan S
Morao and Ercan highlight work from Belew and colleagues that reveals how germ cells repress transcription during nutrient starvation. Animals evolved in environments with variable nutrient availability and one form of adaptation is the delay of reproduction in food shortage conditions. Belew et al. (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202009197) report that in the nematode C. elegans, starvation-induced transcriptional quiescence in germ cells is achieved through a pathway that combines two well-known chromatin compaction mechanisms.
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