Global prevalence of autism and other pervasive developmental disorders.

Global prevalence of autism and other pervasive developmental disorders.
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DOI:
10.1002/aur.239
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发表时间:
2012-06
期刊:
影响因子:
4.7
通讯作者:
Fombonne, Eric
Fombonne, Eric
中科院分区:
医学2区
文献类型:
--
作者:
Elsabbagh, Mayada;Divan, Gauri;Koh, Yun-Joo;Kim, Young Shin;Kauchali, Shuaib;Marcin, Carlos;Montiel-Nava, Cecilia;Patel, Vikram;Paula, Cristiane S.;Wang, Chongying;Yasamy, Mohammad Taghi;Fombonne, Eric

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我们提供了一个系统的审查流行病学调查的自闭症和广泛性发育障碍(PDDs)的世界各地。次要目的是考虑地理、文化/种族和社会经济因素对PDD患病率估计和临床表现的可能影响。根据回顾的证据,自闭症谱系障碍的患病率估计中位数为62/10 000。虽然现有的估计是可变的,但审查的证据不支持地理区域的PDD患病率差异,也不支持种族/文化或社会经济因素的强烈影响。然而,现有的数据集,特别是低收入国家的数据集,检测这种影响的能力受到严重限制。虽然很明显,患病率估计随着时间的推移而增加,这些在不同的邻近和遥远的地区有所不同,这些发现很可能代表了诊断概念的扩大,诊断从其他发育障碍转换为PDD,服务的可用性,以及对自闭症谱系障碍的认识,在外行和专业公众。缺乏来自世界大多数人口的证据表明,迫切需要在低收入和中等收入国家开展进一步的研究和能力建设。Autism Res 2012,5:160-179.© 2012年国际自闭症研究学会,威利期刊公司。
We provide a systematic review of epidemiological surveys of autistic disorder and pervasive developmental disorders (PDDs) worldwide. A secondary aim was to consider the possible impact of geographic, cultural/ethnic, and socioeconomic factors on prevalence estimates and on clinical presentation of PDD. Based on the evidence reviewed, the median of prevalence estimates of autism spectrum disorders was 62/10 000. While existing estimates are variable, the evidence reviewed does not support differences in PDD prevalence by geographic region nor of a strong impact of ethnic/cultural or socioeconomic factors. However, power to detect such effects is seriously limited in existing data sets, particularly in low-income countries. While it is clear that prevalence estimates have increased over time and these vary in different neighboring and distant regions, these findings most likely represent broadening of the diagnostic concets, diagnostic switching from other developmental disabilities to PDD, service availability, and awareness of autistic spectrum disorders in both the lay and professional public. The lack of evidence from the majority of the world's population suggests a critical need for further research and capacity building in low- and middle-income countries. Autism Res 2012, 5: 160–179. © 2012 International Society for Autism Research, Wiley Periodicals, Inc.
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