Regional myocyte size in compensated right ventricular hypertrophy in the ferret.
Regional myocyte size in compensated right ventricular hypertrophy in the ferret.
复制标题
雪貂代偿性右心室肥大的区域肌细胞大小。
DOI：
10.1016/s0022-2828(85)80081-x
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发表时间：
1985
影响因子：
5
通讯作者：
Bishop,SP
中科院分区：
文献类型：
--
作者：
Smith,SH;Bishop,SP
通过比较20只在断奶年龄接受肺动脉结扎术的雪貂和19只未手术的同胞，研究了压力诱导的右心室肥厚对局部心肌细胞大小和形状以及局部心肌湿重的影响。使用分离的肌细胞制剂从6个心肌区域在10个带状和7个非带状雪貂，在右心室流出道和右心室游离壁的细胞体积增加了60%，主要是由于个别肌细胞的横截面积增加。室间隔右侧显示细胞体积中等程度增加，而室间隔左侧对肺动脉结扎术无反应。这些研究结果证实，局部血流动力学的变化产生肥大的个别心肌细胞在选定的区域的心脏和压力诱导的模型涉及增加的横截面积的心肌细胞，细胞长度的变化最小。
The effect of pressure-induced right ventricular hypertrophy on regional myocyte size and shape and regional myocardial wet weight was studied by comparing 20 ferrets which underwent pulmonary artery banding at a weanling age to 19 non-operated siblings. Using isolated myocyte preparations from six myocardial regions in 10 banded and seven non-banded ferrets, a 60% increase in cell volume in the right ventricular outflow tract and the right ventricular free wall was shown to be due primarily to an increased cross-sectional area of individual myocytes. The right side of the interventricular septum exhibited an intermediate increase in cell volume, while the left side of the interventricular septum did not respond to the pulmonary artery banding procedure. These findings confirm that localized hemodynamic changes produce hypertrophy of individual myocytes in selected regions of the heart and that a pressure-induced model of hypertrophy involves an increased cross-sectional area of myocytes, with minimal change in cell length.
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影响因子：
7.3
作者：
BENNETT, A;HENSBY, CN;STAMFORD, IF
通讯作者：
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影响因子：
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作者：
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作者：
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通讯作者：
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作者：
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回肠贮袋-肛门吻合术后的肛门和新直肠功能。
影响因子：
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作者：
Stryker,SJ;Kelly,KA;Phillips,SF;Dozois,RR;BeartJr,RW
通讯作者：
BeartJr,RW