Prospects of Nanostructure Materials and Their Composites as Antimicrobial Agents.
Prospects of Nanostructure Materials and Their Composites as Antimicrobial Agents.
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DOI：
10.3389/fmicb.2018.00422
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发表时间：
2018
影响因子：
5.2
通讯作者：
Chandra P
中科院分区：
文献类型：
--
作者：
Baranwal A;Srivastava A;Kumar P;Bajpai VK;Maurya PK;Chandra P
纳米结构材料（NSM）越来越多地在各种产品中用作抗生素和添加剂的替代品，以赋予杀菌作用。特别是，由于银金属固有的抗菌特性，银纳米粒子（AgNP）作为有效的杀菌剂的使用引起了研究人员的广泛关注。此外，其他纳米材料（碳纳米管、富勒烯、石墨烯、壳聚糖等）也对其抗菌作用进行了研究，以确保其在广泛领域的应用。本综述专门强调具有纳米级抗菌活性的材料，并描述了它们的各种抗菌作用模式。它还需要对 NSM 进行广泛的分类及其在各个领域的应用。例如，在消费品中使用纳米银颗粒，在药物输送中使用纳米金颗粒 (AuNP)。同样，使用氧化锌纳米颗粒 (ZnO-NP) 和二氧化钛纳米颗粒 (TiO2-NP) 作为消费品中的添加剂，以及在医疗产品和废水处理中使用纳米级壳聚糖 (NCH)。此外，本文还简要讨论了抗菌纳米结构材料（aNSM）的现状、当前研究的局限性及其未来前景。为了对此类抗菌药物的最新进展提出各种敏锐的见解，纳入了一个扩展表，该表描述了不同维度的 NSM 对测试微生物的影响及其潜在的广泛应用。
Nanostructured materials (NSMs) have increasingly been used as a substitute for antibiotics and additives in various products to impart microbicidal effect. In particular, use of silver nanoparticles (AgNPs) has garnered huge researchers' attention as potent bactericidal agent due to the inherent antimicrobial property of the silver metal. Moreover, other nanomaterials (carbon nanotubes, fullerenes, graphene, chitosan, etc.) have also been studied for their antimicrobial effects in order ensure their application in widespread domains. The present review exclusively emphasizes on materials that possess antimicrobial activity in nanoscale range and describes their various modes of antimicrobial action. It also entails broad classification of NSMs along with their application in various fields. For instance, use of AgNPs in consumer products, gold nanoparticles (AuNPs) in drug delivery. Likewise, use of zinc oxide nanoparticles (ZnO-NPs) and titanium dioxide nanoparticles (TiO2-NPs) as additives in consumer merchandises and nanoscale chitosan (NCH) in medical products and wastewater treatment. Furthermore, this review briefly discusses the current scenario of antimicrobial nanostructured materials (aNSMs), limitations of current research and their future prospects. To put various perceptive insights on the recent advancements of such antimicrobials, an extended table is incorporated, which describes effect of NSMs of different dimensions on test microorganisms along with their potential widespread applications.
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