Radical pair based magnetic field effects in cells: the importance of photoexcitation conditions and single cell measurements
Radical pair based magnetic field effects in cells: the importance of photoexcitation conditions and single cell measurements
复制标题
细胞中基于自由基对的磁场效应:光激发条件和单细胞测量的重要性
DOI:
10.1101/2022.11.09.515724
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发表时间:
2022
期刊:
影响因子:
--
通讯作者:
Noboru Ikeya
中科院分区:
文献类型:
--
作者:
Jonathan R. Woodward;Noboru Ikeya
A recent publication on the bioRxiv preprint server aims to replicate our observation of magnetic field effects on the autofluorescence of HeLa cells, but is unable to reproduce the effects described in our original work. Here we examine this new study and demonstrate, based on a model of the reaction photocycle, why the differences in the measurement conditions used render the experiment unlikely to be able to observe the originally reported effect. In addition, we highlight substantial problems in the quality of the data in the replicate study and reiterate the advantages of the direct modulation, single cell measurement approach presented in the original work over a more standard statistical approach.
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影响因子:
56.9
作者:
HARKINS, TT;GRISSOM, CB
通讯作者:
GRISSOM, CB
影响因子:
3.7
作者:
D. Yong;A. A. Abdul Rahim;C. Thwin;Sixun Chen;Wei;May Win Naing
通讯作者:
May Win Naing
DOI:
--
发表时间:
2020
期刊:
影响因子:
--
作者:
Hayashi Kouhei;Mizuno Misao;Kandori Hideki;Mizutani Yasuhisa;Jonathan R. Woodward
通讯作者:
Jonathan R. Woodward
DOI:
10.1073/pnas.1118959109
发表时间:
2012-03-27
影响因子:
11.1
作者:
Maeda, Kiminori;Robinson, Alexander J.;Hore, P. J.
通讯作者:
Hore, P. J.
影响因子:
15
作者:
Jones, Alex R.;Scrutton, Nigel S.;Woodward, Jonathan R.
通讯作者:
Woodward, Jonathan R.