MitoBlue: a nontoxic and photostable blue-emitting dye that selectively labels functional mitochondria.
MitoBlue: a nontoxic and photostable blue-emitting dye that selectively labels functional mitochondria.
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DOI:
10.1021/cb500552f
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发表时间:
2014-12-19
影响因子:
4
通讯作者:
Eugenio Vazquez, M.
中科院分区:
文献类型:
--
作者:
Sanchez, Mateo I.;Martinez-Costas, Jose;Mascarenas, Jose L.;Eugenio Vazquez, M.
We report the discovery of a fluorogenic dye, N1,N3-di(2-aminidonaphthalen-6-yl) propane-1,3-diamine, MitoBlue, which selectively stains functional mitochondria while displaying low toxicity, bright blue emission, and high resistance to photobleaching. Additionally, we show that a biotin-labeled MitoBlue derivative can be used as a handle for the delivery of streptavidin-tagged species to the mitochondria.
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影响因子:
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DOI:
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发表时间:
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DOI:
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期刊:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
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