Usefulness of electron-beam computed tomography in arrhythmogenic right ventricular dysplasia. Relationship to electrophysiological abnormalities and left ventricular involvement.
Usefulness of electron-beam computed tomography in arrhythmogenic right ventricular dysplasia. Relationship to electrophysiological abnormalities and left ventricular involvement.
复制标题
电子束计算机断层扫描在致心律失常性右心室发育不良中的作用。
作者：
Hiroshi Tada;Wataru Shimizu;Tohru Ohe;Seiki Hamada;T. Kurita;N. Aihara;S. Kamakura;Makoto Takamiya;Katsuro Shimomura
背景
电子束CT可用于检测心肌脂肪渗透和诊断致心律失常的右室发育不良(ARVD)。ARVD的电子束CT表现具有一定的特征性。然而，这种发生率、它们与电生理异常的关系以及电子束CT在评估左心室受累方面的作用尚不清楚。本研究旨在澄清这些问题。
方法和结果
对14例ARVD患者(ARVD组)、16例年龄和性别匹配的右室增大和/或功能不伴ARVD患者(RV扩大组)和13例对照组(对照组)进行电子束CT检查。比较三组电子束CT异常表现的发生率。此外，我们还检查了电子束CT(CT-A)检测到的心内膜脂肪浸润区(CT-A)和标测电生理检查(EPS-A)发现的电生理异常区域，并比较了ARVD组两者之间的关系。(1)ARVD组心外膜脂肪丰富、低密度小梁、右室游离壁剥落和心肌内脂肪沉积的发生率分别为86%、71%、79%和50%，而RV扩大组和对照组未见上述改变。(2)3例(21%)ARVD患者有左心室脂肪组织受累。(3)CT-A与EPS-A的关系为：CT-A和GT，EPS-A，71%，CT-A=EPS-A，14%，仅EPS-A，14%。
结论
特征性的电子束CT表现通常只在ARVD患者中观察到。电子束CT可用于评价左心室受累程度，并可评估EPS-A。
BACKGROUND
Electron-beam computed tomography (CT) may be useful for detecting myocardial fat infiltration and diagnosing arrhythmogenic right ventricular dysplasia (ARVD). There are several characteristic electron-beam CT findings of ARVD. However, the incidence, their relation to electrophysiological abnormalities, and the usefulness of electron-beam CT for evaluating left ventricular involvement are unknown. This study aimed to clarify these issues.
METHODS AND RESULTS
Electron-beam CT was performed in 14 patients with ARVD (ARVD group), 16 age- and sex-matched patients with right ventricular enlargement and/or dysfunction without ARVD (RV enlargement group), and 13 control subjects (control group). The incidences of abnormal electron-beam CT findings in the three groups were examined. Furthermore, we examined the endocardial fat-infiltrated areas detected by electron-beam CT (CT-A) and electrophysiologically abnormal areas detected in the mapping electrophysiology study (EPS-A) and compared the relationship between them in the ARVD group. (1) The frequencies of abundant epicardial adipose tissue, low-attenuation trabeculations, scalloping of the right ventricular free wall, and intramyocardial fat deposits were 86%, 71%, 79%, and 50%, respectively, in the ARVD group, whereas these findings were not observed in the RV enlargement and control groups. (2) Three ARVD patients (21%) had adipose tissue involvement of the left ventricle. (3) The relationship between CT-A and EPS-A was as follows: CT-A > EPS-A, 71%; CT-A = EPS-A, 14%; and EPS-A only, 14%.
CONCLUSIONS
Characteristic electron-beam CT findings are frequently observed only in patients with ARVD. Electron-beam CT is useful for evaluating for left ventricular involvement and can estimate EPS-A.
影响因子：
4.8
作者：
Higgins,CB;Kaufman,L;Crooks,LE
通讯作者：
Crooks,LE
通过电影计算机断层扫描测量右心室和左心室容积的精度。
影响因子：
37.8
作者：
Reiter,SJ;Rumberger,JA;Feiring,AJ;Stanford,W;Marcus,ML
通讯作者：
Marcus,ML