Magnetic resonance imaging of the cardiovascular system.
Magnetic resonance imaging of the cardiovascular system.
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心血管系统的磁共振成像。
DOI：
10.1016/0002-8703(85)90426-0
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发表时间：
1985
影响因子：
4.8
通讯作者：
Crooks,LE
中科院分区：
文献类型：
--
作者：
Higgins,CB;Kaufman,L;Crooks,LE
磁共振成像（MRI）是一种完全无创的心血管系统可视化技术。1-3利用高强度静态磁场、低强度变化磁场和射频脉冲产生高软组织对比度的人体层析图像。* r5由于生物组织中氢的丰度及其磁共振的效率（每原子序数的最大原子核数），氢（质子）共振已被用于成像。另一方面，通过磁共振过程对体内代谢进行无损监测，需要研究氢以外的生物感兴趣的元素。由于碳13和磷31等非氢元素的丰度和效率较低，用这些元素成像比氢磁共振成像困难得多。这些元素在代谢重要化合物中的分布可以通过高分辨率磁共振波谱而不是成像来研究。即使在生物研究MRI发展的早期阶段，氢成像和各种元素的体内光谱似乎对心血管系统的临床诊断和科学探究都具有巨大的重要性。本报告将回顾过去几年在我们自己和其他几个MRI实验室进行的心血管系统MRI的早期工作。由于MRI是一种新的心血管成像方式，因此在开始时需要对密切相关的物理原理和仪器进行简要回顾。
Magnetic resonance imaging (MRI) is a completely noninvasive technique for the visualization of the cardiovascular system. 1-3 It employs high-strength static magnetic fields, low-strength changing magnetic fields, and radiofrequency pulses to generate tomographic images of the body with high soft tissue contrast.* r5 Because of the abundance of hydrogen in biologic tissues and its efficiency (maximum number of nuclei per atomic number) for magnetic resonance, hydrogen (proton) resonance has been used for imaging. On the other hand, the nondestructive in vivo monitoring of metabolism by the magnetic resonance process requires the study of elements of biologic interest other than hydrogen. Because of the lesser abundance and lower efficiency of nonhydrogen species such as carbon 13 and phosphorus 31, imaging with these elements is much more difficult than hydrogen magnetic resonance imaging. 6 The distribution of these elements in metabolically important compounds can be investigated by high resolution magnetic resonance spectroscopy rather than by imaging. Even at this early juncture in the development of MRI for biologic studies, it seems likely that both hydrogen imaging and in vivo spectroscopy of a variety of elements will have enormous importance for clinical diagnosis and scientific inquiry in the cardiovascular system. This report will review the early work on MRI of the cardiovascular system conducted over the past few years in our own and in several other MRI laboratories. Since MRI is such a new cardiovascular imaging modality, a brief review of closely relevant physical principles and instrumentation is warranted at the outset.
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离体灌注工作大鼠心脏的门控钠 23 核磁共振图像。
DOI：
10.1126/science.7233188
发表时间：
1981
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
DeLayre,JL;Ingwall,JS;Malloy,C;Fossel,ET
通讯作者：
Fossel,ET
31P 核磁共振测量豚鼠灌注心脏的 pH 值。
影响因子：
5
作者：
J. M. Salhany;G. Pieper;S. Wu;G. Todd;F. C. Clayton;R. S. Eliot
通讯作者：
R. S. Eliot
核磁共振成像诱导的 DNA 和染色体损伤测试。
影响因子：
19.7
作者：
S. Wolff;L. Crooks;P. Brown;R. Howard;R. Painter
通讯作者：
R. Painter
通过磷核磁共振检测灌注跳动心脏的局部缺血。
DOI：
--
发表时间：
1977
期刊：
Biochemical and Biophysical Research Communications - BBRC
影响因子：
--
作者：
D. Hollis;R. Nunnally;W. E. Jacobus;G. Taylor
通讯作者：
G. Taylor
缺血心肌中碘造影剂的摄取作为细胞膜完整性丧失的指标。
影响因子：
6
作者：
J. L. Abraham;C. Higgins;J. Newell
通讯作者：
J. Newell