Comparing digital tomosynthesis to cone-beam CT for position verification in patients undergoing partial breast irradiation.
Comparing digital tomosynthesis to cone-beam CT for position verification in patients undergoing partial breast irradiation.
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DOI：
10.1016/j.ijrobp.2008.10.036
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发表时间：
2009-03-01
影响因子：
7
通讯作者：
Yin, Fang-Fang
中科院分区：
文献类型：
--
作者：
Zhang, Junan;Wu, Jackie;Godfrey, Devon J.;Fatunase, Toyosi;Marks, Lawrence B.;Yin, Fang-Fang
关键词：
评估数字断层合成（DTS）技术在加速部分乳房放疗（APBI）患者日常定位中的应用，并比较DTS技术与三维锥束计算机断层扫描（CBCT）的定位精度。10例接受APBI的患者每天接受机载CBCT扫描。利用CBCT投影的子集重建DTS图像切片堆栈。为了优化软组织的可见性，DTS图像斜向重建，使肿瘤床、乳腺组织、肋骨和肺部分离良好。同时重建冠状面和矢状面DTS图像。获取同一患者不同日期DTS图像的平移位移，并与相应CBCT图像的平移位移进行比较。从9例可评估的患者中获得77次CBCT扫描和291次DTS扫描。肿瘤床在斜位DTS扫描中最明显。DTS与CBCT图像的一维定位差异，6例有夹的患者为0.8 ~ 1.7 mm， 3例无夹的患者为1.2 ~ 2.0 mm。由于DTS扫描角度的限制，DTS在离面方向的配准精度低于在面内方向的配准精度。对于接受APBI的患者，DTS定位提供了与CBCT定位相当的日常患者定位精度，同时减少了机械限制和成像剂量。
To evaluate digital tomosynthesis (DTS) technology for daily positioning of patients receiving accelerated partial breast irradiation (APBI) and to compare the positioning accuracy of DTS to 3D cone-beam computed tomography (CBCT). Ten patients who underwent APBI were scanned daily with on-board CBCT. A subset of the CBCT projections was used to reconstruct a stack of DTS image slices. To optimize soft-tissue visibility, the DTS images were reconstructed in oblique directions so that the tumor bed, breast tissue, ribs, and lungs were well separated. Coronal and sagittal DTS images were also reconstructed. Translational shifts of DTS images were obtained on different days from the same patients and were compared to the translational shifts of corresponding CBCT images. Seventy-seven CBCT scans and 291 DTS scans were obtained from 9 evaluable patients. Tumor beds were best visible in the oblique DTS scans. One-dimensional positioning differences between DTS and CBCT images were 0.8 to 1.7 mm for the six patients with clips present and 1.2 to 2.0 mm for the three patients without clips. Due to the limited DTS scan angle, the DTS registration accuracy along the off-plane direction is lower than the accuracy along the in-plane directions. For patients receiving APBI, DTS localization offers comparable accuracy to CBCT localization for daily patient positioning while reducing mechanical constraints and imaging dose.
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DOI：
10.1016/j.ijrobp.2005.06.024
发表时间：
2005-12-01
影响因子：
7
作者：
Vicini, F;Winter, K;McCormick, B
通讯作者：
McCormick, B
影响因子：
3.8
作者：
Yan, Hui;Godfrey, Devon J.;Yin, Fang-Fang
通讯作者：
Yin, Fang-Fang
DOI：
10.1016/j.ijrobp.2006.01.025
发表时间：
2006-05-01
影响因子：
7
作者：
Godfrey, DJ;Yin, FF;Willett, C
通讯作者：
Willett, C
影响因子：
4.6
作者：
GRANT, DG
通讯作者：
GRANT, DG
影响因子：
5
作者：
Poplack, Steven P.;Tosteson, Tor D.;Nagy, Helene M.
通讯作者：
Nagy, Helene M.