Relationship between Olfactory Function and BMI in Normal Weight Healthy Subjects and Patients with Overweight or Obesity.
Relationship between Olfactory Function and BMI in Normal Weight Healthy Subjects and Patients with Overweight or Obesity.
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DOI：
10.3390/nu14061262
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发表时间：
2022-03-16
期刊：
影响因子：
5.9
通讯作者：
Sollai G
中科院分区：
文献类型：
--
作者：
Velluzzi F;Deledda A;Onida M;Loviselli A;Crnjar R;Sollai G
气味通过影响能量平衡和体重，在食物选择和摄入中发挥着至关重要的作用。营养不良问题或饮食行为改变与嗅觉损伤或丧失有关。肥胖流行是一个严重的健康问题，与死亡率和主要身体合并症风险增加有关。肥胖的发病机制复杂且是多因素的，导致其发病率迅速增加的主要因素之一是我们生活的环境，鼓励过度食用富含能量的食物，如饱和脂肪和糖。通过“Sniffin’ Sticks”测试，我们测量了大学医院肥胖中心患者（OC；n = 70）的嗅觉阈值、辨别和识别分数（TDI 分数），并将其与健康正常体重对照（HC；n = 65）进行比较。 OC 患者在区分和识别气味的能力方面表现出比 HC 受试者显着较低的嗅觉功能，即使他们被分别视为女性和男性。对于 OC 患者，无论是按性别划分还是综合考虑，每个受试者的体重指数 (BMI) 和嗅觉得分之间都存在负相关。此外，嗅觉正常的 OC 患者的 BMI 显着低于嗅觉低下的患者。嗅觉减弱可能会导致肥胖，涉及头相反应，延迟获得饱腹感以及过量摄入高能量食物和饮料。
Smell plays a critical role in food choice and intake by influencing energy balance and body weight. Malnutrition problems or modified eating behaviors have been associated with olfactory impairment or loss. The obesity epidemic is a serious health problem associated with an increased risk of mortality and major physical comorbidities. The etiopathogenesis of obesity is complex and multifactorial, and one of the main factors contributing to the rapid increase in its incidence is the environment in which we live, which encourages the overconsumption of foods rich in energy, such as saturated fats and sugars. By means of the “Sniffin’ Sticks” test, we measured the olfactory threshold, discrimination and identification score (TDI score) in patients of the Obesity Center of the University Hospital (OC; n = 70) and we compared them with that of healthy normal weight controls (HC; n = 65). OC patients demonstrated a significantly lower olfactory function than HC subjects both general and specific for the ability to discriminate and identify odors, even when they were considered separately as females and males. For OC patients, a negative correlation was found between body mass index (BMI) and olfactory scores obtained by each subject, both when they were divided according to gender and when they were considered all together. Besides, normosmic OC patients showed a significantly lower BMI than hyposmic ones. A reduced sense of smell may contribute to obesity involving the responses of the cephalic phase, with a delay in the achievement of satiety and an excessive intake of high-energy foods and drinks.
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影响因子：
56.9
作者：
HUBERT, HB;FABSITZ, RR;FEINLEIB, M
通讯作者：
FEINLEIB, M
影响因子：
8.8
作者：
Belfort-DeAguiar, Renata;Seo, Dongju
通讯作者：
Seo, Dongju
影响因子：
3.3
作者：
Connor, Erin E.;Zhou, Yang;Liu, George E.
通讯作者：
Liu, George E.
影响因子：
5.4
作者：
Bolhuis, Dieuwerke P.;Lakemond, Catriona M. M.;de Graaf, Cees
通讯作者：
de Graaf, Cees
DOI：
10.1111/j.1749-6632.1989.tb20975.x
发表时间：
1989-06-30
影响因子：
5.2
作者：
FERRIS, AM;DUFFY, VB
通讯作者：
DUFFY, VB