Levels and correlates of physical activity and capacity among HIV-infected compared to HIV-uninfected individuals.
Levels and correlates of physical activity and capacity among HIV-infected compared to HIV-uninfected individuals.
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DOI：
10.1371/journal.pone.0262298
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发表时间：
2022
期刊：
影响因子：
3.7
通讯作者：
Olsen MF
中科院分区：
文献类型：
--
作者：
Kitilya B;PrayGod G;Peck R;Changalucha J;Jeremiah K;Kavishe BB;Friis H;Filteau S;Faurholt-Jepsen D;Krogh-Madsen R;Brage S;Olsen MF
在感染艾滋病毒的人中，体育锻炼可以提高体力、生活质量，并降低患非传染性疾病的风险。在撒哈拉以南非洲，感染艾滋病毒的患者报告说，与未感染艾滋病毒的人相比，他们的活跃程度较低。在坦桑尼亚的姆万扎，我们评估了接受抗逆转录病毒治疗(ART)的HIV感染者与未感染HIV的个体相比，客观测量的体力活动和能力的水平和相关性。我们在年龄和性别频率匹配的新诊断的艾滋病毒感染者和未感染艾滋病毒的个体中进行了一项横断面研究。收集社会人口学数据、人体测量学、CD4计数、血红蛋白水平和C反应蛋白(CRP)。体力活动能量消耗(PAEE)被评估为体力活动的衡量标准，而睡眠心率(SHR)和握力被评估为体能的衡量标准。使用多变量线性回归来评估与体力活动和能力相关的因素。共有272名艾滋病毒感染者和119名未感染艾滋病毒的人参与了这项研究，他们的平均年龄为39岁，其中60%是女性。与非HIV感染者相比，HIV感染者的体能和运动能力较差：PAEE降低(-7.3KJ/kg/d，95%CI：-11.2，-3.3)，SHR升高(7.7次/min，95%CI：10.1，5.3)，握力降低(-4.7 kg，95%CI：-6.8，-2.8)。在HIV感染者中，低体重指数、中重度贫血、低CD4计数和高CRP与较低的体力活动和能力有关。在未感染艾滋病毒的人中，腹型肥胖和中度贫血与较低的体力活动和能力有关。感染艾滋病毒的参与者的体力活动水平和能力低于未感染艾滋病毒的参与者。体力活动和能力的相关性因艾滋病毒状况而异。需要在保健设施中有效地提供艾滋病毒及相关疾病的管理。在这些人口中促进体育活动的干预措施对于改善他们的健康和减少非传染性疾病的风险将是重要的。
In the HIV-infected individuals, physical activity improves physical strength, quality of life and reduces the risk of developing non-communicable diseases. In Sub-Saharan Africa, HIV-infected patients report being less active compared to HIV-uninfected individuals. We assessed the levels and correlates of objectively measured physical activity and capacity among HIV-infected antiretroviral therapy (ART)-naive individuals compared to HIV-uninfected individuals in Mwanza, Tanzania. We conducted a cross-sectional study among newly diagnosed HIV-infected ART-naive individuals and HIV-uninfected individuals frequency-matched for age and sex. Socio-demographic data, anthropometrics, CD4 counts, haemoglobin level, and C-reactive protein (CRP) were collected. Physical activity energy expenditure (PAEE) was assessed as measure of physical activity whereas sleeping heart rate (SHR) and grip strength were assessed as measures of physical capacity. Multivariable linear regression was used to assess the correlates associated with physical activity and capacity. A total of 272 HIV-infected and 119 HIV-uninfected individuals, mean age 39 years and 60% women participated in the study. Compared to HIV-uninfected individuals, HIV-infected had poorer physical activity and capacity: lower PAEE (-7.3 kj/kg/day, 95% CI: -11.2, -3.3), elevated SHR (7.7 beats/min, 95%CI: 10.1, 5.3) and reduced grip strength (-4.7 kg, 95%CI: -6.8, -2.8). In HIV-infected individuals, low body mass index, moderate-severe anaemia, low CD4 counts and high CRP were associated with lower physical activity and capacity. In HIV-uninfected individuals, abdominal obesity and moderate anaemia were associated with lower physical activity and capacity. HIV-infected participants had lower levels of physical activity and capacity than HIV-uninfected participants. Correlates of physical activity and capacity differed by HIV status. Management of HIV and related conditions needs to be provided effectively in health care facilities. Interventions promoting physical activity in these populations will be of importance to improve their health and reduce the risk of non-communicable diseases.
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影响因子：
158.5
作者：
MACALLAN, DC;NOBLE, C;GRIFFIN, GE
通讯作者：
GRIFFIN, GE
DOI：
10.1111/tmi.12852
发表时间：
2017-05
期刊：
Tropical medicine & international health : TM & IH
影响因子：
--
作者：
Bernard C;Dabis F;de Rekeneire N
通讯作者：
de Rekeneire N
影响因子：
3.1
作者：
Loney, Tom;Standage, Martyn;Cumming, Sean P.
通讯作者：
Cumming, Sean P.
影响因子：
3.7
作者：
Kerkhoff AD;Wood R;Cobelens FG;Gupta-Wright A;Bekker LG;Lawn SD
通讯作者：
Lawn SD
影响因子：
2.2
作者：
Freedson, PS;Miller, K
通讯作者：
Miller, K