Exploration of photoprotective and antibiotic activity of wild Polypodiaceae ferns from Costa Rica.
Exploration of photoprotective and antibiotic activity of wild Polypodiaceae ferns from Costa Rica.
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哥斯达黎加野生水龙骨科蕨类植物的光保护和抗菌活性研究。
DOI：
10.1038/s41598-023-50281-3
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发表时间：
2024-01-18
影响因子：
4.6
通讯作者：
中科院分区：
文献类型：
--
作者：
皮肤疾病影响着全世界数百万人。治疗皮肤疾病的方法有限，如白癜风、牛皮癣和特应性皮炎（湿疹）。中美洲蕨类植物是对抗这些疾病的生物活性代谢物的潜在来源。目前，Polypodium leucotomos Poir。是唯一一种用于商业目的的。在这项工作中，我们评估了20种哥斯达黎加野生蕨类植物提取物中皮肤生物活性化合物奎宁酸和绿原酸的浓度。并对野生蕨类植物粗提物的抑菌性能和防晒系数进行了评价。我们发现20种中有19种具有上述化合物的重要浓度或抗菌特性。此外，大多数样品的SPF值高于金黄色葡萄球菌根茎。我们还研究了蕨类植物在不同遮荫条件下的驯化，发现培养条件对代谢物产量有显著影响。适应环境。到目前为止，我们证明了本研究中包括的各种蕨类植物是治疗皮肤病的潜在来源。
Skin disorders affect millions of people all over the world. There are limited options to treat dermal illnesses such as vitiligo, psoriasis, and atopic dermatitis (eczema). Central American ferns are a potential source of bioactive metabolites against those diseases. Currently, Polypodium leucotomos Poir. is the only one being commercially utilized for this purpose. In this work, we evaluated the concentration of the skin bioactive compounds: quinic and chlorogenic acid, in the extract of 20 wild ferns from Costa Rica. We also evaluated the antimicrobial capabilities of the crude extracts of wild ferns and the sun protection factor (SPF) of the extracts. We found 19 out of 20 have either an important concentration of the compounds mentioned above or antimicrobial properties. Also, most samples result in higher SPF than P. aureum’s rhizome. We also have studied the fern acclimatization, at different shading conditions, finding a significant influence of the culturing conditions on metabolite production. After acclimatization. So far, we demonstrate that various ferns included in this study are a potential source of treatments for skin conditions.
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影响因子：
6.5
作者：
Dellacecca, Emilia R.;Cosgrove, Cormac;Mukhatayev, Zhussipbek;Akhtar, Suhail;Engelhard, Victor H.;Rademaker, Alfred W.;Knight, Katherine L.;Le Poole, I. Caroline
通讯作者：
Le Poole, I. Caroline
影响因子：
2.3
作者：
Glensk, Michal;Tichaczek-Goska, Dorota;Wojnicz, Dorota
通讯作者：
Wojnicz, Dorota
影响因子：
2.3
作者：
Martin, SL;Davis, R;Martin, CE
通讯作者：
Martin, CE
影响因子：
3.9
作者：
Lou, Zaixiang;Wang, Hongxin;Wang, Zhouping
通讯作者：
Wang, Zhouping
DOI：
10.1016/j.ijantimicag.2010.03.016
发表时间：
2010-07-01
影响因子：
10.8
作者：
Sader, Helio S.;Farrell, David J.;Jones, Ronald N.
通讯作者：
Jones, Ronald N.