Endoscopic Features of Gastric Epithelial Neoplasm of Fundic Gland Mucosa Lineage.

Endoscopic Features of Gastric Epithelial Neoplasm of Fundic Gland Mucosa Lineage.
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DOI:
10.3390/diagnostics12112666
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发表时间:
2022-11-02
期刊:
影响因子:
3.6
通讯作者:
Nagahara, Akihito
Nagahara, Akihito
中科院分区:
医学3区
文献类型:
--
作者:
Matsumoto, Kohei;Ueyama, Hiroya;Yao, Takashi;Iwano, Tomoyo;Yamamoto, Momoko;Utsunomiya, Hisanori;Uchida, Ryota;Abe, Daiki;Oki, Shotaro;Suzuki, Nobuyuki;Ikeda, Atsushi;Yatagai, Noboru;Akazawa, Yoichi;Takeda, Tsutomu;Ueda, Kumiko;Asaoka, Daisuke;Hojo, Mariko;Nagahara, Akihito

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胃底腺粘膜系上皮性肿瘤(GEN-FGML)的内镜特征尚未得到很好的研究。我们的目的是阐明内镜下GEN-FGML的特点和胃底腺型胃腺癌(GA-FG)和胃底腺粘膜型胃腺癌(GA-FGM)之间的差异。共62个GEN-FGML病变,包括52个GA-FG和10个GA-FGM,使用内镜和临床病理结果进行回顾性分析,以提供使用白色光成像(WLI)和放大内镜窄带成像(M-NBI)的诊断价值的信息。GA-FG在WLI中常表现为发白的粘膜下肿瘤(SMT)形状,血管扩张,分支结构和背景粘膜无萎缩性变化,在M-NBI中分界线(DL)不清楚,隐窝开口和介入部分(IP)扩张,微血管无明显不规则。GA-FGM在WLI中常表现为淡红色、隆起的病变,在M-NBI中表现为明显的DL、IP扩张和不规则的微血管模式。至于M-NBI诊断,5个GA-FGM病变符合癌症诊断标准,而GA-FG病变均不符合相同标准。我们强调GEN-FGML的内镜特征,并且在WLI和M-NBI诊断中结合病变颜色和形态可能区分GA-FG和GA-FGM。
The endoscopic features of gastric epithelial neoplasms of fundic gland mucosa lineage (GEN-FGML) have not been well investigated. We aimed to clarify the endoscopic features of GEN-FGML and differences between gastric adenocarcinoma of the fundic gland type (GA-FG) and fundic gland mucosa type (GA-FGM). A total of 62 GEN-FGML lesions, including 52 GA-FG and 10 GA-FGM, were retrospectively analyzed using endoscopic and clinicopathological findings to provide information of diagnostic value using white light imaging (WLI) and magnifying endoscopy with narrow-band imaging (M-NBI). GA-FG frequently presented with a whitish, submucosal tumor (SMT) shape with dilated vessels with branching architecture and background mucosa without atrophic change in WLI, an indistinct demarcation line (DL), dilatation of the crypt opening and intervening part (IP), and microvessels without distinct irregularity in M-NBI. GA-FGM frequently presented as a reddish, elevated lesion in WLI, with a distinct DL, dilatation of the IP, and an irregular microvascular pattern in M-NBI. As for an M-NBI diagnosis, five GA-FGM lesions met the diagnostic criteria for cancer, whereas none of the GA-FG lesions met the same criteria. We highlight the endoscopic features of GEN-FGML, and the differentiation between GA-FG and GA-FGM might be possible by combination of lesion color and morphology in WLI and M-NBI diagnoses.
基础gland粘膜谱系的胃上皮肿瘤:与基础gland类型的胃腺癌相关的新分类的提案。
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发表时间: 2010-05-01
影响因子: 5.6
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DOI: 10.1055/a-1220-6389
发表时间: 2020-10
影响因子: 2.6
作者:
Matsumoto K;Ueyama H;Yao T;Abe D;Oki S;Suzuki N;Ikeda A;Yatagai N;Akazawa Y;Komori H;Takeda T;Matsumoto K;Hojo M;Nagahara A
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DOI: 10.3760/cma.j.cn112151-20190720-00404
发表时间: 2020-04-08
期刊: Zhonghua bing li xue za zhi = Chinese journal of pathology
影响因子: --
作者:
Sun, W W;Zhang, L;Da, Q
通讯作者: Da, Q