Electroencephalographic sleep and natural killer activity in depressed patients and control subjects.

Electroencephalographic sleep and natural killer activity in depressed patients and control subjects.
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抑郁症患者和对照受试者的脑电图睡眠和自然杀伤活性。

DOI:
10.1097/00006842-199201000-00002
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发表时间:
1992
影响因子:
3.3
通讯作者:
Gillin,JC
Gillin,JC
中科院分区:
医学3区
文献类型:
--
作者:
Irwin,M;Smith,TL;Gillin,JC

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抑郁症患者的自然杀伤细胞(NK)活性降低与其他抑郁症状的严重程度无关。本研究通过探讨抑郁症患者(n= 23)和对照组(n= 17)的睡眠客观脑电图(EEG)评估和NK活性值之间的关系,扩展了这些发现。睡眠脑电图参数总睡眠时间,睡眠效率,非REM睡眠的持续时间分别与NK活性在抑郁症患者和对照组呈正相关,表现出类似的睡眠量和NK活性之间的关系在不同的群体。这些观察结果支持这一假设,即睡眠措施与NK细胞毒性,独立的抑郁症状的严重程度或情绪障碍的存在的影响。
: Insomnia is associated with a reduction of natural killer (NK) activity in depression independent of the severity of other depressive symptoms. This study extends these findings by exploring the relationship between objective electroencephalographic (EEG) assessment of sleep and values of NK activity in depressed patients (n= 23) and in control subjects (n= 17). The sleep EEG parameters total sleep time, sleep efficiency, and duration of nonREM sleep were each positively correlated with NK activity in the depressed patients and in the control subjects, demonstrating similar relationships between the amount of sleep and NK activity in the separate groups. These observations support the hypothesis that sleep measures are associated with NK cytotoxicity, independent of the effects of severity of depressive symptoms or the presence of a mood disorder.
下丘脑-免疫相互作用:通过损伤下丘脑前部来神经调节自然杀伤活性。
DOI: --
发表时间: 1984
期刊: Immunology
影响因子: 6.4
作者:
Cross,RJ;Markesbery,WR;Brooks,WH;Roszman,TL
通讯作者: Roszman,TL
DOI: 10.1152/ajpregu.1984.246.6.r994
发表时间: 1984-01-01
影响因子: --
作者:
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通讯作者: CHEDID, L
DOI: 10.1016/0006-3223(88)90272-7
发表时间: 1988-06-01
影响因子: 10.6
作者:
IRWIN, M;DANIELS, M;WEINER, H
通讯作者: WEINER, H
精神分裂症和抑郁症中的裂解效应细胞功能
DOI: 10.1016/0165-5728(88)90050-1
发表时间: 1988
影响因子: 3.3
作者:
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DOI: 10.1001/archpsyc.1985.01790340021003
发表时间: 1985
影响因子: --
作者:
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通讯作者: M. Schuckit