The impact of bone microstructure on the field distribution of electrostimulative implants

The impact of bone microstructure on the field distribution of electrostimulative implants
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骨微结构对电刺激植入物场分布的影响

DOI:
10.1109/embc.2015.7319158
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发表时间:
2015
期刊:
2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
影响因子:
--
通讯作者:
van Rienen U
van Rienen U
中科院分区:
--
文献类型:
--
作者:
Zimmermann U;van Rienen U

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自20世纪80年代以来,已经开发了几种电刺激技术的方法来加速骨科治疗期间的骨再生。这些技术已被证明可以在治疗骨折和骨病的同时增加骨形成。然而,电参数大多是将骨组织视为均匀材料的经验研究结果。特别是松质骨,这是一种新的电刺激全髋关节翻修系统的目标,具有多孔、不均匀的微观结构。目前的工作调查数值的电场分布在该组织内使用显微镜的计算机断层扫描的小骨样品。这些扫描的三维X射线吸收值与来自文献的电导率值应用不同的相关方法相关。与均匀材料内的电场相比,在包括大部分骨形成细胞的结构内可以观察到强升高。
Since the 1980s several methods of electrostimulative techniques have been developed to accelerate bone regeneration during orthopedic treatment. These techniques have proven to provide increased bone formation while curing fractures and bone diseases. The electric parameters, however, are mostly results of empiric research regarding the bone tissue as homogeneous material. Especially cancellous bone, which is the objective of a new electrostimulative total hip revision system, has a porous, inhomogeneous microstructure. The present work investigates numerically the electric field distribution within this tissue using microscopic computer tomography scans of small bone samples. The 3-dimensional X-ray absorption values of these scans are correlated with conductivity values from literature applying different correlation approaches. Compared to electric fields within a homogeneous material strong elevations can be observed within the structures which include most of the bone forming cells.
DOI: 10.1002/bem.21879
发表时间: 2014
影响因子: 1.9
作者:
Souffrant R;Kluess D;Ellenrieder M;Mittelmeier W;van Rienen U;Bader R
通讯作者: Bader R
DOI: 10.1088/0031-9155/41/11/003
发表时间: 1996-11-01
影响因子: 3.5
作者:
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通讯作者: Gabriel, C
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发表时间: 2010-02-01
影响因子: 4.6
作者:
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