An early report from newly established laboratory-based influenza surveillance in Lao PDR.

An early report from newly established laboratory-based influenza surveillance in Lao PDR.
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LAO PDR中新成立的基于实验室的流感监测的早期报告。

DOI:
10.1111/j.1750-2659.2009.00120.x
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发表时间:
2010-03
影响因子:
4.4
通讯作者:
Bryant JE
Bryant JE
中科院分区:
医学4区
文献类型:
--
作者:
Vongphrachanh P;Simmerman JM;Phonekeo D;Pansayavong V;Sisouk T;Ongkhamme S;Bryce GT;Corwin A;Bryant JE

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Please cite this paper as:Vongphrachanh P,Simmerman JM,Phonekeo D,Pansayavong V,Sisouk T,Ongkhamme S,Bryce GT,Corwin A,Bryant JE.来自老挝新建立的基于实验室的流感监测的早期报告。流感和其他呼吸道病毒4(2),47-52。 背景在2007年之前,关于老挝流感负担的信息很少。 我们报告的数据来自老挝人民民主共和国建立的第一个基于实验室的流感监测系统。 方法首都万象的三家医院于2007年开始监测门诊患者的流感样疾病(ILI),并于2008年扩大到包括住院肺炎患者。 采集鼻/咽拭子标本,并在Luminex® 100× MAP IS仪器(Qiagen,新加坡)上通过多重ID‐TagTM呼吸道病毒检测试剂盒(RVP)检测流感病毒和其他呼吸道病毒。 结果2007年1月至2008年12月期间,526例ILI门诊患者中有287例(54.6%)至少有一种呼吸道病毒阳性。 流感是最常见的,确定了63例(12.0%)甲型流感和92例(17.5%)B流感阳性患者。2008年,79例住院肺炎患者中有6例(7.6%)甲型流感阳性,4例(5.1%)B流感阳性。<5岁的儿童占门诊患者病毒感染的19%,占肺炎住院患者的38%。  结论:我们的研究结果首次提供了老挝发热性呼吸道疾病和肺炎住院患者流感负担的文献资料。 实施基于实验室的流感监测需要在基础设施和培训方面进行大量投资。然而,家禽中A/H5 N1禽流感的持续爆发和2009年A(H1N1)流感大流行毒株的出现进一步突出了在发展中国家建立和维持流感监测的重要性。
Please cite this paper as: Vongphrachanh P, Simmerman JM, Phonekeo D, Pansayavong V, Sisouk T, Ongkhamme S, Bryce GT, Corwin A, Bryant JE. An early report from newly established laboratory‐based influenza surveillance in Lao PDR. Influenza and Other Respiratory Viruses 4(2), 47–52. Background  Prior to 2007, little information was available about the burden of influenza in Laos. We report data from the first laboratory‐based influenza surveillance system established in the Lao People’s Democratic Republic. Methods  Three hospitals in the capital city of Vientiane began surveillance for influenza‐like illness (ILI) in outpatients in 2007 and expanded to include hospitalized pneumonia patients in 2008. Nasal/throat swab specimens were collected and tested for influenza and other respiratory viruses by multiplex ID‐TagTM respiratory viral panel (RVP) assay on a Luminex® 100× MAP IS instrument (Qiagen, Singapore). Results  During January 2007 to December 2008, 287 of 526 (54·6%) outpatients with ILI were positive for at least one respiratory virus. Influenza was most commonly identified, with 63 (12·0%) influenza A and 92 (17·5%) influenza B positive patients identified. In 2008, six of 79 (7·6%) hospitalized pneumonia patients were positive for influenza A and four (5·1%) were positive for influenza B. Children <5 years represented 19% of viral infections in outpatients and 38% of pneumonia inpatients. Conclusion  Our results provide the first documentation of influenza burden among patients with febrile respiratory illness and pneumonia requiring hospitalization in Laos. Implementing laboratory‐based influenza surveillance requires substantial investments in infrastructure and training. However, continuing outbreaks of avian influenza A/H5N1 in poultry and emergence of the 2009 influenza A(H1N1) pandemic strain further underscore the importance of establishing and maintaining influenza surveillance in developing countries.
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