Mechanisms and Clinical Application of Tetramethylpyrazine (an Interesting Natural Compound Isolated from Ligusticum Wallichii): Current Status and Perspective.

Mechanisms and Clinical Application of Tetramethylpyrazine (an Interesting Natural Compound Isolated from Ligusticum Wallichii): Current Status and Perspective.
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四甲基吡嗪(从川芎中分离出的一种有趣的天然化合物)的机制和临床应用:现状和展望

DOI:
10.1155/2016/2124638
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发表时间:
2016
影响因子:
--
通讯作者:
Chen K
Chen K
中科院分区:
生物学2区
文献类型:
--
作者:
Zhao Y;Liu Y;Chen K

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川芎嗪是从川芎中提取的天然化合物,在我国广泛应用于心脑血管疾病已有近40年的历史。由于其在多系统尤其是心血管系统中的作用,其药理作用、临床应用以及结构修饰已引起广泛关注。本文就其作用机制、临床应用现状及合成衍生物作一简要综述。
Tetramethylpyrazine, a natural compound from Ligusticum wallichii (Chuan Xiong), has been extensively used in China for cardiovascular and cerebrovascular diseases for about 40 years. Because of its effectiveness in multisystems, especially in cardiovascular, its pharmacological action, clinical application, and the structural modification have attracted broad attention. In this paper its mechanisms of action, the clinical status, and synthetic derivatives will be reviewed briefly.
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