UTGB/medaka: genomic resource database for medaka biology.
UTGB/medaka: genomic resource database for medaka biology.
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DOI：
10.1093/nar/gkm765
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发表时间：
2008-01
影响因子：
14.9
通讯作者：
Morishita, Shinichi
中科院分区：
文献类型：
--
作者：
Ahsan, Budrul;Kobayashi, Daisuke;Yamada, Tomoyuki;Kasahara, Masahiro;Sasaki, Shin;Saito, Taro L.;Nagayasu, Yukinobu;Doi, Koichiro;Nakatani, Yoichiro;Qu, Wei;Jindo, Tomoko;Shimada, Atsuko;Naruse, Kiyoshi;Toyoda, Atsushi;Kuroki, Yoko;Fujiyama, Asao;Sasaki, Takashi;Shimizu, Atsushi;Asakawa, Shuichi;Shimizu, Nobuyoshi;Hashimoto, Shin-Ichi;Yang, Jun;Lee, Yongjun;Matsushima, Kouji;Sugano, Sumio;Sakaizumi, Mitsuru;Narita, Takanori;Ohishi, Kazuko;Haga, Shinobu;Ohta, Fumiko;Nomoto, Hisayo;Nogata, Keiko;Morishita, Tomomi;Endo, Tomoko;Shin-I, Tadasu;Takeda, Hiroyuki;Kohara, Yuji;Morishita, Shinichi
Medaka （Oryzias latipes）是一种原产于东亚的小型产卵淡水硬骨鱼，已成为发育遗传学和进化生物学的优秀模型系统。medaka基因组序列草案（700 Mb）于2007年6月报道，其大量基因组资源已通过东京大学基因组浏览器medaka （UTGB/medaka）数据库向公众开放。该数据库提供了基本的基因组信息，如预测基因、表达序列标签（ESTs）、鸟嘌呤/胞嘧啶（GC）含量、重复序列和比较基因组学，以及独特的数据资源，包括(i) 2473个遗传标记和扩增这些标记的实验证实的PCR引物，（ii） 142 414个细菌人工染色体（BAC）和217 344个fosmid末端序列，分别达到整个基因组克隆覆盖率的15.0和11.1倍。（iii）在两个medaka近交菌株基因组之间检测到16 519 460个单核苷酸多态性（snp）和2 859 905个插入/缺失；（iv）基因表达（SAGE）标记的841 235个5 '端序列分析确定了基因组上的344 266个转录起始位点。UTGB/medaka可从http://medaka.utgenome.org/获得
Medaka (Oryzias latipes) is a small egg-laying freshwater teleost native to East Asia that has become an excellent model system for developmental genetics and evolutionary biology. The draft medaka genome sequence (700 Mb) was reported in June 2007, and its substantial genomic resources have been opened to the public through the University of Tokyo Genome Browser Medaka (UTGB/medaka) database. This database provides basic genomic information, such as predicted genes, expressed sequence tags (ESTs), guanine/cytosine (GC) content, repeats and comparative genomics, as well as unique data resources including (i) 2473 genetic markers and experimentally confirmed PCR primers that amplify these markers, (ii) 142 414 bacterial artificial chromosome (BAC) and 217 344 fosmid end sequences that amount to 15.0- and 11.1-fold clone coverage of the entire genome, respectively, and were used for draft genome assembly, (iii) 16 519 460 single nucleotide polymorphisms (SNPs), and 2 859 905 insertions/deletions detected between two medaka inbred strain genomes and (iv) 841 235 5′-end serial analyses of gene-expression (SAGE) tags that identified 344 266 transcription start sites on the genome. UTGB/medaka is available at: http://medaka.utgenome.org/
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影响因子：
4.4
作者：
Sasaki, Takashi;Shimizu, Atsushi;Shimizu, Nobuyoshi
通讯作者：
Shimizu, Nobuyoshi
影响因子：
2.9
作者：
HINEGARDNER, R;ROSEN, DE
通讯作者：
ROSEN, DE
影响因子：
64.8
作者：
Kasahara, Masahiro;Naruse, Kiyoshi;Kohara, Yuji
通讯作者：
Kohara, Yuji
影响因子：
64.8
作者：
Matsuda, M;Nagahama, Y;Sakaizumi, M
通讯作者：
Sakaizumi, M
影响因子：
46.9
作者：
Hashimoto, S;Suzuki, Y;Matsushima, K
通讯作者：
Matsushima, K