Reliability of repeated cognitive assessment of dementia using a brief computerized battery.

Reliability of repeated cognitive assessment of dementia using a brief computerized battery.
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DOI:
10.1177/1533317511411907
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发表时间:
2011-06
期刊:
American journal of Alzheimer's disease and other dementias
影响因子:
--
通讯作者:
Giordani B
Giordani B
中科院分区:
其他
文献类型:
--
作者:
Hammers D;Spurgeon E;Ryan K;Persad C;Heidebrink J;Barbas N;Albin R;Frey K;Darby D;Giordani B

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本研究的目的是评估短期的稳定性和可靠性,一个简短的计算机认知电池在确定的痴呆类型。患者接受两次计算机化电池给药,间隔约2小时,并进行常规神经心理学测试。通过共识会议将患者临床分类为健康对照(n= 23)、轻度认知障碍(n= 20)、阿尔茨海默病(n= 52)、路易体痴呆(n= 10)或额颞叶痴呆(n= 9)。在两个CogState测试管理中,最小的实践效果是明显的。在工作记忆任务中,所有组都有小幅度的改善,健康对照组对联想学习的准确性表现出轻微的练习效果。结论:在确定的痴呆症,管理的CogState任务似乎敏感的认知障碍痴呆症。重复给药还提供了可接受的稳定性和重测信度,尽管存在认知挑战,但在短的重测间隔下具有最小的实践影响。
The aim of this study was to evaluate the short-term stability and reliability of a brief computerized cognitive battery in established dementia types. Patients were administered the computerized battery twice with administrations approximately two hours apart, with intervening conventional neuropsychological tests. Patients were classified clinically, via consensus conference as healthy controls (n= 23), Mild Cognitive Impairment (n= 20), Alzheimer’s disease (n= 52), dementia with Lewy Bodies (n= 10), or Frontotemporal dementia (n= 9). Minimal practice effects were evident across the two CogState test administrations. Small magnitude improvements were seen across all groups on a working memory task, and healthy controls showed a mild practice effect on the accuracy of associative learning. Conclusions: In established dementia, administration of the CogState tasks appears sensitive to cognitive impairment in dementia. Repeat administration also provided acceptable stability and test-retest reliability with minimal practice effects at short test-retest intervals despite intervening cognitive challenges.
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