Academy of Breastfeeding Medicine founder's lecture 2008: breastfeeding--an extrauterine link between mother and child.

Academy of Breastfeeding Medicine founder's lecture 2008: breastfeeding--an extrauterine link between mother and child.
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母乳喂养医学学会创始人 2008 年演讲:母乳喂养——母亲与孩子之间的宫外联系。

DOI:
10.1089/bfm.2009.0004
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发表时间:
2009
期刊:
Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine
影响因子:
--
通讯作者:
Walker,WAllan
Walker,WAllan
中科院分区:
--
文献类型:
--
作者:
Rautava,Samuli;Walker,WAllan

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除了为成长中的婴儿提供近乎最佳的营养组合外,母乳还含有多种生物活性分子,已知这些分子可以保护婴儿免受传染病的侵害并调节固有肠道微生物群的组成。在母乳中也发现了越来越多调节婴儿免疫生理学的因素。我们认为,通过母乳进行的这种早期免疫调节对于婴儿健康至关重要,并且可以解释流行病学数据表明母乳可以降低婴儿期和以后生命中免疫炎症性疾病的风险。本文综述了有关母乳中转化生长因子-β 在增强健康免疫成熟和降低疾病风险方面的作用的科学数据。
In addition to a near-optimal combination of nutrients for the growing infant, breastmilk contains a wide array of bioactive molecules that are known to protect the infant against infectious disease and modulate the composition of the indigenous intestinal microbiota. A growing number of factors that modulate the infant's immunophysiology have also been identified in breastmilk. We suggest that this early immunomodulation via breastmilk is vital for infant health and may explain the epidemiological data indicating that breastmilk reduces the risk of immunoinflammatory conditions in infancy and also later in life. The body of scientific data regarding the role of transforming growth factor-β in breastmilk in enhancing healthy immune maturation and reducing the risk of disease is reviewed in this article.
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