Chromosome Jumping: A Long Range Cloning Technique

Chromosome Jumping: A Long Range Cloning Technique
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染色体跳跃:长距离克隆技术

DOI:
10.1007/978-1-4615-7081-3_10
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发表时间:
1988
期刊:
Genetic engineering
影响因子:
--
通讯作者:
H. Lehrach
H. Lehrach
中科院分区:
--
文献类型:
--
作者:
A. Poustka;H. Lehrach

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Genetics, the correlation of changes in the phenotype with heritable changes in the DNA of cells and organisms, and the localization of these changes to genes and ultimately DNA sequences, offers a direct and unbiased way to identify and analyze the basic functions required for life at all levels of complexity. In contrast, molecular biology provides a set of powerful techniques to analyze DNA sequences, to identify gene products, and to understand molecular mechanisms. It is therefore not unexpected, that the molecular analysis of genes defined by mutations has been essential to understand many functions required for the formation and continual existence of organisms.
含有小鼠 6 号染色体和人类 7 号染色体上基因的同源盒的遗传和细胞遗传学定位。
DOI: 10.1002/j.1460-2075.1986.tb04585.x
发表时间: 1986
期刊: The EMBO journal
影响因子: --
作者:
Bućan,M;Yang-Feng,T;Colberg-Poley,AM;Wolgemuth,DJ;Guenet,JL;Francke,U;Lehrach,H
通讯作者: Lehrach,H
DOI: 10.1073/pnas.81.21.6812
发表时间: 1984-01-01
期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子: --
作者:
COLLINS, FS;WEISSMAN, SM
通讯作者: WEISSMAN, SM
通过体内重组和选择从噬菌体文库中纯化基因组序列。
DOI: 10.1093/nar/11.8.2427
发表时间: 1983
影响因子: 14.9
作者:
Seed,B
通讯作者: Seed,B