Performance Investigation of a Hospital-grade X-ray Tube-based Differential Phase-contrast Cone Beam CT System.
Performance Investigation of a Hospital-grade X-ray Tube-based Differential Phase-contrast Cone Beam CT System.
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DOI：
10.1117/12.911400
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发表时间：
2012-02-12
期刊：
影响因子：
--
通讯作者：
Conover D
中科院分区：
文献类型：
--
作者：
Yu Y;Ning R;Cai W;Liu J;Conover D
差分相位衬度技术有望成为CT成像领域的下一个突破口。虽然传统的基于吸收的X射线CT成像在区分软组织方面效率不高，但相位对比技术具有很大的优势，因为它能够利用物体的相位信息产生更高的对比度图像。我们的长期目标是开发一种基于门架级X射线管差分相位对比锥束CT(DPC-CBCT)技术，在不增加剂量水平的情况下，能够在软组织成像中获得更高的对比噪声比(CNR)。在去年建成的微焦点系统的基础上，设计并搭建了台式医用X线管DPC-CBCT系统。DPC-CBCT系统由医用X射线管和源栅、高分辨率探测器、旋转模架、位相栅和分析栅组成。三维(3-D)位相系数被重建，为我们提供了比传统CBCT扫描更高的CNR，但剂量水平相当的图像。研究了该系统的三个重要方面：a)重建图像相对于剂量水平的CNR的系统性能；b)不同的相位步进方案(即5步到8步)对重建图像的影响；以及c)体模的放大倍率或位置对图像质量的影响，主要是对CNR的影响。这些调查是通过体模研究完成的。
Differential phase contrast technique could be the next breakthrough in the field of CT imaging. While traditional absorption-based X-ray CT imaging is inefficient at differentiating soft tissues, phase-contrast technique offers great advantage as being able to produce higher contrast images utilizing the phase information of objects. Our long term goal is to develop a gantry-based hospital-grade X-ray tube differential phase contrast cone-beam CT (DPC-CBCT) technology which is able to achieve higher contrast noise ratio (CNR) in soft tissue imaging without increasing the dose level. Based on the micro-focus system built last year, a bench-top hospital-grade X-ray tube DPC-CBCT system is designed and constructed. The DPC-CBCT system consists of an X-ray source, i.e. a hospital-grade X-ray tube and a source grating, a high-resolution detector, a rotating phantom holder, a phase grating and an analyzer grating. Three-dimensional (3-D) phase-coefficients are reconstructed, providing us with images enjoying higher CNR than, yet equivalent dose level to, a conventional CBCT scan. Three important aspects of the system are investigated: a) The The system’s performance in term of CNR of the reconstruction image with regard to dose levels, b) the impacts of different phase stepping schemes, i.e. 5 steps to 8 steps, in term of CNR on the reconstruction images, and c) the influence of magnification or position of the phantom on image quality, chiefly CNR. The investigations are accomplished via phantom study.
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影响因子：
19.6
作者：
Pfeiffer, F;Weitkamp, T;David, C
通讯作者：
David, C
DOI：
10.1117/12.878492
发表时间：
2011-03-16
期刊：
Proceedings of SPIE--the International Society for Optical Engineering
影响因子：
--
作者：
Yu Y;Ning R;Cai W
通讯作者：
Cai W
影响因子：
3.5
作者：
Chou, Cheng-Ying;Anastasio, Mark A.;Zhong, Zhong
通讯作者：
Zhong, Zhong
影响因子：
1.6
作者：
Snigirev, A;Snigireva, I;Schelokov, I
通讯作者：
Schelokov, I
影响因子：
1.6
作者：
MOMOSE, A;TAKEDA, T;ITAI, Y
通讯作者：
ITAI, Y