EchoBASE: an integrated post-genomic database for Escherichia coli.

EchoBASE: an integrated post-genomic database for Escherichia coli.
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DOI:
10.1093/nar/gki028
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发表时间:
2005-01-01
影响因子:
14.9
通讯作者:
Thomas GH
Thomas GH
中科院分区:
生物学2区
文献类型:
--
作者:
Misra RV;Horler RS;Reindl W;Goryanin II;Thomas GH

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EchoBASE(http:www.ecoli-york.org)是一个关系数据库,旨在包含和操作来自使用模型细菌大肠杆菌K-12的后基因组实验的信息。其目的是整理来自广泛来源的信息,为大约1500种尚未证实细胞功能的基因产物的功能提供线索。该数据库建立在对菌株MG 1655的更新基因组序列的增强注释以及实验数据与大肠杆菌基因及其产物的关联上。可以在EchoBASE中进行的实验包括蛋白质组学研究,微阵列数据,蛋白质-蛋白质相互作用数据,结构数据和生物信息学研究。EchoBASE还包含来自这种微生物的“孤儿”酶活性的注释信息,以帮助表征催化这些难以捉摸的生化反应的蛋白质。
EchoBASE (http://www.ecoli-york.org) is a relational database designed to contain and manipulate information from post-genomic experiments using the model bacterium Escherichia coli K-12. Its aim is to collate information from a wide range of sources to provide clues to the functions of the approximately 1500 gene products that have no confirmed cellular function. The database is built on an enhanced annotation of the updated genome sequence of strain MG1655 and the association of experimental data with the E.coli genes and their products. Experiments that can be held within EchoBASE include proteomics studies, microarray data, protein–protein interaction data, structural data and bioinformatics studies. EchoBASE also contains annotated information on ‘orphan’ enzyme activities from this microbe to aid characterization of the proteins that catalyse these elusive biochemical reactions.
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影响因子: 11.1
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