Neoadjuvant therapy for resectable pancreatic cancer.
Neoadjuvant therapy for resectable pancreatic cancer.
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DOI:
10.4251/wjgo.v9.i12.457
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发表时间:
2017-12-15
影响因子:
3
通讯作者:
Molinari M
中科院分区:
文献类型:
--
作者:
Rahman SH;Urquhart R;Molinari M
The use of neoadjuvant therapies has played a major role for borderline resectable and locally advanced pancreatic cancers (PCs). For this group of patients, preoperative chemotherapy or chemoradiation has increased the likelihood of surgery with negative resection margins and overall survival. On the other hand, for patients with resectable PC, the main rationale for neoadjuvant therapy is that the overall survival with current strategies is unsatisfactory. There is a consensus that we need new treatments to improve the overall survival and quality of life of patients with PC. However, without strong scientific evidence supporting the theoretical advantages of neoadjuvant therapies, these potential benefits might turn out not to be worth the risk of tumors progression while waiting for surgery. The focus of this paper is to provide the readers an overview of the most recent evidence on this subject.
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影响因子:
3.7
作者:
Katz MH;Varadhachary GR;Fleming JB;Wolff RA;Lee JE;Pisters PW;Vauthey JN;Abdalla EK;Sun CC;Wang H;Crane CH;Lee JH;Tamm EP;Abbruzzese JL;Evans DB
通讯作者:
Evans DB
影响因子:
2.9
作者:
Hurton, Scott;MacDonald, Frank;Molinari, Michele
通讯作者:
Molinari, Michele
影响因子:
3.6
作者:
Valeri, S.;Borzomati, D.;Coppola, R.
通讯作者:
Coppola, R.
影响因子:
3.7
作者:
Roland CL;Yang AD;Katz MH;Chatterjee D;Wang H;Lin H;Vauthey JN;Pisters PW;Varadhachary GR;Wolff RA;Crane CH;Lee JE;Fleming JB
通讯作者:
Fleming JB
影响因子:
3.7
作者:
Katz, Matthew H. G.;Merchant, Nipun B.;Pisters, Peter W. T.
通讯作者:
Pisters, Peter W. T.