Supercritical carbon dioxide extraction of bioactive compounds from Ampelopsis grossedentata stems: process optimization and antioxidant activity.
Supercritical carbon dioxide extraction of bioactive compounds from Ampelopsis grossedentata stems: process optimization and antioxidant activity.
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DOI：
10.3390/ijms12106856
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发表时间：
2011
影响因子：
5.6
通讯作者：
Xu P
中科院分区：
文献类型：
--
作者：
Wang Y;Ying L;Sun D;Zhang S;Zhu Y;Xu P
Supercritical carbon dioxide (SC-CO2) extraction of bioactive compounds including flavonoids and phenolics from Ampelopsis grossedentata stems was carried out. Extraction parameters such as pressure, temperature, dynamic time and modifier, were optimized using an orthogonal array design of L9 (34), and antioxidant activities of the extracts were evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay and ferrous ion chelating (FIC) assay. The best conditions obtained for SC-CO2 extraction of flavonoids was 250 bar, 40 °C, 50 min, and with a modifier of methanol/ethanol (1:3, v/v), and that for phenolics extraction was 250 bar, 40 °C, 50 min, and with a modifier of methanol/ethanol (1:1, v/v). Meantime, flavonoids and phenolics were found to be mainly responsible for the DPPH scavenging activity of the extracts, but not for the chelating activity on ferrous ion according to Pearson correlation analysis. Furthermore, several unreported flavonoids such as apigenin, vitexin, luteolin, etc., have been detected in the extracts from A. grossedentata stems.
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影响因子：
4.1
作者：
Du, QZ;Chen, P;Winterhalter, P
通讯作者：
Winterhalter, P
影响因子：
8.8
作者：
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Mirtajaldini, Mansour
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通讯作者：
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6.1
作者：
Lang, QY;Wai, CM
通讯作者：
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