Standard Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) Study system for evaluation of stereoscopic color fundus photographs and fluorescein angiograms: SCORE Study Report 9.
Standard Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) Study system for evaluation of stereoscopic color fundus photographs and fluorescein angiograms: SCORE Study Report 9.
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DOI：
10.1001/archophthalmol.2010.193
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发表时间：
2010-09
期刊：
影响因子：
--
通讯作者：
SCORE Study Research Group
中科院分区：
文献类型：
--
作者：
Blodi BA;Domalpally A;Scott IU;Ip MS;Oden NL;Elledge J;Warren K;Altaweel MM;Kim JE;Van Veldhuisen PC;SCORE Study Research Group
描述 SCORE 研究参与者的立体彩色眼底照片和荧光素血管造影分级的程序和再现性。在 84 个临床中心拍摄的标准化立体眼底照片和荧光素血管造影照片由中央阅片中心的分级人员进行评估。根据眼底照片评估视网膜静脉阻塞（RVO）类型、视网膜增厚面积和视网膜出血面积；通过荧光素血管造影测量荧光素渗漏面积和毛细血管无灌注面积。时间再现性包括连续 3 年随机选择的专用眼底照片子集（60 名受试者）和荧光素血管造影照片（40 名受试者）的年度重新评级。同期再现性涉及每月对最近评估的眼底照片（n=73）中随机选择的 5% 进行重新分级。在 3 次年度降级中，RVO 类型和视网膜增厚存在的分级者一致性大于 90%。 3 年中视网膜增厚面积的组内相关性 (ICC) 范围为 0.39 至 0.64，视网膜出血面积的组内相关性 (ICC) 范围为 0.87 至 0.96。荧光素渗漏面积的 ICC 范围为 0.66 至 0.75，毛细血管无灌注面积的 ICC 范围为 0.94 至 0.97。除了视网膜增厚面积（ICC，0.84）之外，所有变量的同期再现性结果与时间再现性结果相似。 SCORE 研究的眼底照相和荧光素血管造影分级程序具有可重复性，可用于 RVO 的多中心纵向研究。在评估视网膜增厚区域时发生系统性时间漂移。
To describe the procedures and reproducibility for grading stereoscopic color fundus photographs and fluorescein angiograms of participants in the SCORE Study. Standardized stereoscopic fundus photographs and fluorescein angiograms taken at 84 clinical centers were evaluated by graders at a central reading center. Type of retinal vein occlusion (RVO), area of retinal thickening, and area of retinal hemorrhage are evaluated from fundus photographs; area of fluorescein leakage and area of capillary nonperfusion are measured on fluorescein angiography. Temporal reproducibility consisted of annual regrading of a randomly selected dedicated subset of fundus photographs (60 subjects) and fluorescein angiograms (40 subjects) for 3 successive years. Contemporaneous reproducibility involved monthly regrading of a 5% random selection of recently evaluated fundus photographs (n=73). The intergrader agreement for RVO type and presence of retinal thickening was greater than 90% in the 3 annual regrades. The intraclass correlation (ICC) for area of retinal thickening in the 3 years ranged from 0.39 to 0.64 and for area of retinal hemorrhage, 0.87 to 0.96. The ICC for area of fluorescein leakage ranged from 0.66 to 0.75 and for capillary nonperfusion, 0.94 to 0.97. The contemporaneous reproducibility results were similar to those of temporal reproducibility for all variables except area of retinal thickening (ICC, 0.84). The fundus photography and fluorescein angiography grading procedures for the SCORE Study are reproducible and can be used for multicenter longitudinal studies of RVO. A systematic temporal drift occurred in evaluating area of retinal thickening.
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影响因子：
4.4
作者：
Hubbard, Larry D.;Danis, Ronald P.;Pugliese, Michael F.
通讯作者：
Pugliese, Michael F.
影响因子：
--
作者：
Domalpally, Amitha;Blodi, Barbara A.;Scott, Ingrid U.;Ip, Michael S.;Oden, Neal L.;Lauer, Andreas K.;VanVeldhuisen, Paul C.
通讯作者：
VanVeldhuisen, Paul C.
影响因子：
13.7
作者：
Ip MS;Oden NL;Scott IU;VanVeldhuisen PC;Blodi BA;Figueroa M;Antoszyk A;Elman M;SCORE Study Investigator Group
通讯作者：
SCORE Study Investigator Group
影响因子：
13.7
作者：
Scott IU;Blodi BA;Ip MS;Vanveldhuisen PC;Oden NL;Chan CK;Gonzalez V;SCORE Study Investigator Group
通讯作者：
SCORE Study Investigator Group