Revisiting the role of oxygen therapy in cardiac patients.
Revisiting the role of oxygen therapy in cardiac patients.
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DOI:
10.1016/j.jacc.2010.04.052
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发表时间:
2010-09-21
影响因子:
24
通讯作者:
Sinoway, Lawrence I.
中科院分区:
文献类型:
--
作者:
Moradkhan, Raman;Sinoway, Lawrence I.
Over the past century, lacking the precision of today’s advanced technology, multiple studies provided conflicting data on the effects of oxygen therapy in normoxic cardiac patients. More importantly, no randomized, blinded and controlled studies have shown a benefit of such treatment. Yet the use of supplemental oxygen is widespread in cardiac patients. In these conditions, inadvertent hyperoxia commonly occurs because of concerns to ensure sufficient oxygenation and because hyperoxia is not perceived to be detrimental. In recent years, there has been mounting evidence demonstrating the potential adverse effects of hyperoxia on the cardiovascular system. In this report, we review data examining the effects of supplemental oxygen in normoxic patients with acute presentations of coronary artery disease (CAD). It is also the aim of this report to emphasize the point that oxygen therapy might have major adverse physiologic effects that must be considered when it is employed.
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