Trends, patterns and psychological influences on COVID-19 vaccination intention: Findings from a large prospective community cohort study in England and Wales (Virus Watch).

Trends, patterns and psychological influences on COVID-19 vaccination intention: Findings from a large prospective community cohort study in England and Wales (Virus Watch).
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DOI:
10.1016/j.vaccine.2021.09.066
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发表时间:
2021-11-26
期刊:
影响因子:
5.5
通讯作者:
Virus Watch Collaborative
Virus Watch Collaborative
中科院分区:
医学3区
文献类型:
--
作者:
Byrne T;Patel P;Shrotri M;Beale S;Michie S;Butt J;Hawkins N;Hardelid P;Rodger A;Aryee A;Braithwaite I;Fong WLE;Fragaszy E;Geismar C;Kovar J;Navaratnam AMD;Nguyen V;Hayward A;Aldridge RW;Virus Watch Collaborative

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在英格兰和威尔士,接种COVID-19疫苗的意愿非常高。大多数最初不愿意接受COVID-19疫苗的人后来改变了主意。年轻人和一些少数民族的人更有可能不确定或计划拒绝接种COVID-19疫苗。对疫苗的看法和对COVID-19疾病严重程度的看法都会影响疫苗接种意向。疫苗接种意愿是任何疫苗接种计划成功的关键,同时也是疫苗供应和获得的关键。与其他国家相比,英格兰和威尔士的公众接种COVID-19疫苗的意愿很高,但种族、社会和年龄组之间的疫苗接种率差异引发了担忧。对英格兰和威尔士未来家庭社区队列研究参与者的在线调查(病毒观察)。疫苗接种意愿通过个体参与者对“如果提供COVID-19疫苗,你会接受吗?”的回答来衡量,于二零二零年十二月及二零二一年二月收集。使用因子分析对2021年1月收集的13项问卷的回答进行分析,以调查心理对疫苗接种意愿的影响。2020年12月的调查回应率为56%(20,785/36,998),2021年2月为53%(20,590/38,727),两个时间点均有14,880名成年人报告。2020年12月,1,469名(10%)参与者回答“否”或“不确定”。在这些人中,有1,266人(86%)在2021年2月之前改变了主意,并回答“是”或“已经接种了COVID-19疫苗”。接种疫苗的意愿在所有族裔群体和社会剥夺程度上都有所增加。年龄与疫苗接种意愿的相关性最强,2020年12月,16-24岁的人比65-74岁的人更有可能回答“不确定”或“否”而不是“是”(OR:4.63,95% CI:3.42,6.27 & OR 7.17 95% CI:4.26,12.07)和2021年2月(OR:27.92 95% CI:13.79,56.51 & OR 17.16 95% CI:4.12,71.55)。随着时间的推移,种族和疫苗接种意愿之间的关联减弱,但并没有消失。研究表明,疫苗和疾病相关的心理因素都会影响疫苗接种意向。在2020年12月不愿意或打算拒绝接种COVID-19疫苗的成年人中,五分之四(86%)在2021年2月改变了主意,计划接受或已经接受疫苗。
Intention to take a COVID-19 vaccine when offered is very high in England and Wales. Most people who were initially reluctant to accept a COVID-19 vaccine went on to change their mind. Young adults and people from some minority ethnic groups are more likely to be uncertain or plan to refuse a COVID-19 vaccine. Both perceptions of vaccines and perceptions of COVID-19 illness severity shape vaccine intention. Vaccination intention is key to the success of any vaccination programme, alongside vaccine availability and access. Public intention to take a COVID-19 vaccine is high in England and Wales compared to other countries, but vaccination rate disparities between ethnic, social and age groups has led to concern. Online survey of prospective household community cohort study participants across England and Wales (Virus Watch). Vaccination intention was measured by individual participant responses to ‘Would you accept a COVID-19 vaccine if offered?’, collected in December 2020 and February 2021. Responses to a 13-item questionnaire collected in January 2021 were analysed using factor analysis to investigate psychological influences on vaccination intention. Survey response rate was 56% (20,785/36,998) in December 2020 and 53% (20,590/38,727) in February 2021, with 14,880 adults reporting across both time points. In December 2020, 1,469 (10%) participants responded ‘No’ or ‘Unsure’. Of these people, 1,266 (86%) changed their mind and responded ‘Yes’ or ‘Already had a COVID-19 vaccine’ by February 2021. Vaccination intention increased across all ethnic groups and levels of social deprivation. Age was most strongly associated with vaccination intention, with 16–24-year-olds more likely to respond “Unsure” or “No” versus “Yes” than 65–74-year-olds in December 2020 (OR: 4.63, 95 %CI: 3.42, 6.27 & OR 7.17 95 %CI: 4.26, 12.07 respectively) and February 2021 (OR: 27.92 95 %CI: 13.79, 56.51 & OR 17.16 95 %CI: 4.12, 71.55). The association between ethnicity and vaccination intention weakened, but did not disappear, over time. Both vaccine- and illness-related psychological factors were shown to influence vaccination intention. Four in five adults (86%) who were reluctant or intending to refuse a COVID-19 vaccine in December 2020 had changed their mind in February 2021 and planned to accept, or had already accepted, a vaccine.
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