Response surface optimization of the water immersion extraction and macroporous resin purification processes of anhydrosafflor yellow B from Carthamus tinctorius L.
Response surface optimization of the water immersion extraction and macroporous resin purification processes of anhydrosafflor yellow B from Carthamus tinctorius L.
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红花脱水红花黄B水浸提取及大孔树脂纯化工艺的响应面优化。
DOI：
10.1111/1750-3841.15374
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发表时间：
2020-08
影响因子：
3.9
通讯作者：
Yu He
中科院分区：
文献类型：
--
作者：
Peng Zhou;Yijia Fangma;Weifeng Jin;Zhan Jin;Xiaohong Li;Yu He
In this study,based on a developed high performance liquid chromatographic quantitative method, the suitable extraction and purification conditions of anhydrosafflor yellow B (AHSYB) from safflower were determined by response surface methodology. The optimal water immersion extraction parameters were as follows: liquid to solid ratio of 22:1; extraction temperature of 75 °C; extraction time of 35 min. Under these conditions, the maximum extraction yield of AHSYB reached 0.465%. The aqueous extract was further purified by HPD-300 macroporous resin. The optimum adsorption conditions were: pH 2.8; adsorption flow rate of 1.9 mL/min; solution concentration of 0.06 g/mL. The optimum desorption conditions were: ethanol concentrations of 74%; desorption flow rate of 1.6 mL/min; elution volume of 4.4 BV. Under these conditions, the maximum adsorption ratio and desorption ratio reached 1.095 and 0.906 mg/g, respectively. The content of AHSYB reached 6.83%, which was 2.91 times higher than that before purification. PRACTICAL APPLICATION: The suitable conditions for water immersion extraction and macroporous resin purification of AHSYB are first determined, which facilitates the further utilization of AHSYB as a food and drug.
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DOI：
10.1016/j.jchromb.2015.09.013
发表时间：
2015-10
期刊：
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
影响因子：
--
作者：
S. Yue;Liang Wu;C. Qu;Yuping Tang;Yi Jin;Shujiao Li;Juan Shen;Xu-qin Shi;Chenxiao Shan
通讯作者：
S. Yue;Liang Wu;C. Qu;Yuping Tang;Yi Jin;Shujiao Li;Juan Shen;Xu-qin Shi;Chenxiao Shan
DOI：
10.3390/molecules22111894
发表时间：
2017-11-03
期刊：
Molecules (Basel, Switzerland)
影响因子：
--
作者：
Chang CW;Yen CC;Wu MT;Hsu MC;Wu YT
通讯作者：
Wu YT
影响因子：
5.3
作者：
Kaur, Prabhjot;Gupta, R. C.;Pandey, Devendra Kumar
通讯作者：
Pandey, Devendra Kumar
影响因子：
8.8
作者：
C. Villa;J. Costa;M. B. Oliveira;I. Mafra
通讯作者：
C. Villa;J. Costa;M. B. Oliveira;I. Mafra
DOI：
--
发表时间：
2013-12
期刊：
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
影响因子：
--
作者：
Yan-wen Sun;Yu He;Ruping Zhang;Jia-wei Huang;Man-cang Gu
通讯作者：
Yan-wen Sun;Yu He;Ruping Zhang;Jia-wei Huang;Man-cang Gu