Biomarkers in aortic dissection: Diagnostic and prognostic value from clinical research.

Biomarkers in aortic dissection: Diagnostic and prognostic value from clinical research.
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DOI:
10.1097/cm9.0000000000002719
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发表时间:
2024-02-05
影响因子:
6.1
通讯作者:
Wang, Lixin
Wang, Lixin
中科院分区:
医学2区
文献类型:
--
作者:
Zhao, Yufei;Fu, Weiguo;Wang, Lixin

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主动脉夹层是一种危及生命的疾病,其诊断主要依赖于影像学检查,而用于检测或监测的可靠生物标志物仍在研究中。技术的最新进展提供了一个前所未有的机会,可以识别出具有临床价值的生物标志物,包括蛋白质、核糖核酸(RNA)和脱氧核糖核酸(DNA),用于易感患者的病理变化的早期检测、发病后的床边快速诊断以及主要在主动脉夹层的个性化和定制血管内治疗概念内的上级治疗方案。
Aortic dissection is a life-threatening condition for which diagnosis mainly relies on imaging examinations, while reliable biomarkers to detect or monitor are still under investigation. Recent advances in technologies provide an unprecedented opportunity to yield the identification of clinically valuable biomarkers, including proteins, ribonucleic acids (RNAs), and deoxyribonucleic acids (DNAs), for early detection of pathological changes in susceptible patients, rapid diagnosis at the bedside after onset, and a superior therapeutic regimen primarily within the concept of personalized and tailored endovascular therapy for aortic dissection.
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