Relationship between optical coherence tomography retinal parameters and visual acuity in diabetic macular edema.
Relationship between optical coherence tomography retinal parameters and visual acuity in diabetic macular edema.
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DOI：
10.1016/j.ophtha.2010.03.051
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发表时间：
2010-12
期刊：
影响因子：
13.7
通讯作者：
Sadda SR
中科院分区：
文献类型：
--
作者：
Alasil T;Keane PA;Updike JF;Dustin L;Ouyang Y;Walsh AC;Sadda SR
目的探讨光学相干断层扫描(OCT)测量糖尿病黄斑水肿患者视网膜形态与视力的关系。回顾性横断面研究。共有67例(67眼)糖尿病黄斑水肿(DME)患者接受了层状OCT成像。记录每个患者的最佳矫正Snellen视力。使用名为“OCTOR”的定制软件对每个患者的原始导出Stratus OCT图像进行分析，该软件允许在单独的B超上精确定位预先指定的边界。计算神经感觉性视网膜和视网膜下液的厚度、体积和密度。此外，对光感受器外段(POS)厚度进行了定量。OCT测量视网膜形态和视力。OCTOR测量的中央亚场厚度、强度、视网膜下积液体积、POS厚度和对数视觉锐度(最小分辨率的对数)之间的Spearman系数r分别为0.3428(p=0.005)、-0.2658(p=0.03)、-0.2683(p=0.38)、-0.3703(p=0.002)。逐步选择的多变量模型显示，在总研究人群中，累积R2为0.4305，未治疗组和先前聚焦激光组的R2分别为0.4999和0.7628。对DME眼的OCT特征进行亚分析和量化似乎是有价值的。特别是，光感受器外节厚度似乎是DME患者功能和视力的重要预测指标。
To investigate the relationship between optical coherence tomography (OCT)-derived measurements of retinal morphology and visual acuity in patients with diabetic macular edema. Retrospective cross-sectional study. A total of 67 consecutive patients (67 eyes) with diabetic macular edema (DME) who underwent Stratus OCT imaging. Best-corrected Snellen visual acuity was recorded for each patient. Raw exported Stratus OCT images for each patient were analyzed using custom software entitled “OCTOR”, which allows the precise positioning of prespecified boundaries on individual B-scans. Thickness, volume, and intensity were calculated for neurosensory retina and subretinal fluid. In addition, photoreceptor outer segment (POS) thickness was quantified. OCT-derived measurements of retinal morphology and visual acuity. The Spearman coefficient values (r) of the correlation between OCTOR-derived measurements of central subfield thickness, intensity, subretinal fluid (SRF) volume, POS thickness and logMAR visual acuities (logarithm of the minimum angle of resolution) were 0.3428 (p=0.005), -0.2658 (p=0.03), -0.2683 (p=0.38), -0.3703 (p=0.002) respectively. Multivariate models with stepwise selection revealed a cumulative R2 of 0.4305 in the total study population, with R2 of 0.4999 and 0.7628 in the untreated and prior focal laser groups, respectively. Subanalysis and quantification of OCT features in eyes with DME appears to be of value. In particular, photoreceptor outer segment thickness appears to be an important predictor of function and visual acuity in patients with DME.
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DOI：
10.1097/00006982-200212000-00012
发表时间：
2002-12-01
影响因子：
3.3
作者：
Goebel, W;Kretzchmar-Gross, T
通讯作者：
Kretzchmar-Gross, T
通过光学相干断层扫描鉴别不同病因引起的黄斑水肿
影响因子：
4.2
作者：
Catier, A;Tadayoni, R;Massin, P
通讯作者：
Massin, P
DOI：
10.1111/j.1600-0420.2005.00387.x
发表时间：
2005-02-01
期刊：
ACTA OPHTHALMOLOGICA SCANDINAVICA
影响因子：
--
作者：
Ozdemir, H;Karacorlu, M;Karacorlu, S
通讯作者：
Karacorlu, S
影响因子：
4.2
作者：
Hayashi, Hisako;Yamashiro, Kenji;Yoshimura, Nagahisa
通讯作者：
Yoshimura, Nagahisa
影响因子：
13.7
作者：
Martidis, A;Duker, JS;Baumal, C
通讯作者：
Baumal, C