Salmonella Typhi Stool Shedding by Patients With Enteric Fever and Asymptomatic Chronic Carriers in an Endemic Urban Setting.
Salmonella Typhi Stool Shedding by Patients With Enteric Fever and Asymptomatic Chronic Carriers in an Endemic Urban Setting.
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DOI:
10.1093/infdis/jiab476
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发表时间:
2021-12-20
期刊:
影响因子:
--
通讯作者:
Qadri F
中科院分区:
文献类型:
--
作者:
Khanam F;Darton TC;Meiring JE;Kumer Sarker P;Kumar Biswas P;Bhuiyan MAI;Hasan Rajib N;Tonks S;Pollard AJ;Clemens JD;Qadri F
The burden of Salmonella enterica serotype Typhi (S. Typhi) shedding in stool and its contribution to transmission in endemic settings is unknown. During passive surveillance S. Typhi shedding was seen during convalescence in 332 bacteremic patient with typhoid, although none persisted at 1-year follow-up. Anti–virulence capsule (Vi)–immunoglobulin (Ig) G titers were measured in age-stratified cohort of serosurveillance participants. Systematic stool sampling of 303 participants with high anti–Vi-IgG titers identified 1 asymptomatic carrier with shedding. These findings suggest that ongoing S. Typhi transmission in this setting is more likely to occur from acute convalescent cases, although better approaches are needed to identify true chronic carriers in the community to enable typhoid elimination.
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影响因子:
6.4
作者:
LEVINE, MM;BLACK, RE;LANATA, C
通讯作者:
LANATA, C
影响因子:
3.7
作者:
Dongol, Sabina;Thompson, Corinne N.;Baker, Stephen
通讯作者:
Baker, Stephen
影响因子:
11.8
作者:
Waddington, Claire S.;Darton, Thomas C.;Pollard, Andrew J.
通讯作者:
Pollard, Andrew J.
DOI:
10.1038/nrmicro2490
发表时间:
2011-01
期刊:
Nature reviews. Microbiology
影响因子:
--
作者:
通讯作者:
--
DOI:
10.2105/ajph.54.3.477
发表时间:
1964-01-01
期刊:
AMERICAN JOURNAL OF PUBLIC HEALTH AND THE NATIONS HEALTH
影响因子:
--
作者:
BOKKENHEUSER, V
通讯作者:
BOKKENHEUSER, V