A method to assess seasonality of urinary tract infections based on medication sales and google trends.

A method to assess seasonality of urinary tract infections based on medication sales and google trends.
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DOI:
10.1371/journal.pone.0076020
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发表时间:
2013
期刊:
影响因子:
3.7
通讯作者:
Hanslik T
Hanslik T
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Rossignol L;Pelat C;Lambert B;Flahault A;Chartier-Kastler E;Hanslik T

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尽管尿路感染(UTI)是一种非常常见的疾病,但对其在社区中的季节性知之甚少。使用可用的UTI代理构建的多个时间序列来估计UTI的季节性。使用了基于两个数据库的8个时间序列:2000年至2012年期间法国一组药店报告的泌尿系抗菌药物销售情况,以及2004年至2012年期间法国、德国、意大利、美国、中国、澳大利亚和巴西在Google搜索引擎上对UTI相关术语的搜索趋势。夏季和冬季之间的差异进行了统计评估与曼-惠特尼检验。我们评估的季节性应用谐波产品频谱快速傅立叶变换。八分之七的时间序列显示,与冬季相比,夏季的药物销售或网络搜索量显着增加,幅度从8%到20%不等。这八个时间序列的周期为一年。今年夏天,法国的UTI药物销售量以及法国、美国、德国、意大利和中国的谷歌搜索量都出现了年度增长。在巴西和澳大利亚,谷歌搜索量在夏季有所增加。UTI的年度季节性在七个不同的国家得到证明,在夏季达到高峰。
Despite the fact that urinary tract infection (UTI) is a very frequent disease, little is known about its seasonality in the community. To estimate seasonality of UTI using multiple time series constructed with available proxies of UTI. Eight time series based on two databases were used: sales of urinary antibacterial medications reported by a panel of pharmacy stores in France between 2000 and 2012, and search trends on the Google search engine for UTI-related terms between 2004 and 2012 in France, Germany, Italy, the USA, China, Australia and Brazil. Differences between summers and winters were statistically assessed with the Mann-Whitney test. We evaluated seasonality by applying the Harmonics Product Spectrum on Fast Fourier Transform. Seven time series out of eight displayed a significant increase in medication sales or web searches in the summer compared to the winter, ranging from 8% to 20%. The eight time series displayed a periodicity of one year. Annual increases were seen in the summer for UTI drug sales in France and Google searches in France, the USA, Germany, Italy, and China. Increases occurred in the austral summer for Google searches in Brazil and Australia. An annual seasonality of UTIs was evidenced in seven different countries, with peaks during the summer.
DOI: 10.1111/j.1469-0691.2010.03327.x
发表时间: 2011-06-01
影响因子: 14.2
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