Parameters of Capsulorrhexis and Intraocular Lens Decentration After Femtosecond and Manual Capsulotomies in High Myopic Patients With Cataracts.

Parameters of Capsulorrhexis and Intraocular Lens Decentration After Femtosecond and Manual Capsulotomies in High Myopic Patients With Cataracts.
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DOI:
10.3389/fmed.2021.640269
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发表时间:
2021
影响因子:
3.9
通讯作者:
Shentu X
Shentu X
中科院分区:
医学3区
文献类型:
--
作者:
Zhu Y;Shi K;Yao K;Wang Y;Zheng S;Xu W;Chen P;Yu Y;Shentu X

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目的:比较高度近视白内障患者飞秒激光撕囊术和手动连续环形撕囊术后的撕囊参数和人工透镜偏心。方法:这是一项前瞻性连续非随机对照队列研究。选择眼轴长度> 26.0 mm的患者,分为飞秒激光撕囊术(FS)组和手动连续环形撕囊术(CCC)组。5名经验丰富的超声乳化术外科医生进行了所有手术。记录术中并发症和术后眼前节摄影。在术后1周、1个月和2年测量眼内透镜偏心、撕囊面积、圆形度和囊重叠。采用独立样本t检验或Mann-Whitney U检验、方差分析、Pearson卡方检验和斯皮尔曼等级相关检验确定参数的组间差异。结果:共108例142眼,FS组68眼,CCC组74眼。术后1周、1个月、2年时,CCC组撕囊面积均明显大于FS组(P < 0.05),而环形度无明显差异。FS组各时间点的完全重叠率均显著高于CCC组(P < 0.05)。CCC组前房深度与撕囊面积呈显著正相关(R = 0.25,P = 0.04),FS组前房深度与撕囊面积无相关性(P > 0.05)。在前房深度>3 mm的患者中,CCC组的囊袋-人工透镜(IOL)重叠在术后所有测量时间点均小于FS组(P < 0.05)。术后2年CCC组人工晶状体偏心度明显大于FS组(P < 0.05)。结论:在前房深度超过3 mm的高度近视白内障患者中,飞秒激光晶状体囊切开术可以实现更好的撕囊尺寸和居中。由于FS组的晶状体囊切开术更精确,晶状体囊-IOL重叠更好,飞秒激光晶状体囊切开术导致IOL更好的长期居中。
Purpose: To compare the parameters of capsulorrhexis and intraocular lens decentration after femtosecond laser capsulotomy and manual continuous curvilinear capsulorrhexis in high myopic patients with cataracts. Methods: This is a prospective consecutive non-randomized comparative cohort study. Selected patients with axial length > 26.0 mm were divided into femtosecond laser capsulotomy (FS) group and manual continuous curvilinear capsulorrhexis (CCC) group. Five experienced phacoemulsification surgeons conducted all surgeries. Intraoperative complications and post-operative anterior segment photography were recorded. Intraocular lens decentration, area of capsulorrhexis, circularity, and capsule overlap were measured at 1 week, 1 month, and 2 years after surgery. Between group differences of parameters were determined with independent-sample t-test or the Mann–Whitney U-test, analysis of variance test, Pearson chi-square test, and Spearman rank correlation test. Results: The study included 142 eyes (108 patients), 68 eyes in the FS group, and 74 eyes in the CCC group. At 1 week, 1 month, and 2 years after surgery, the area of capsulorrhexis in the CCC group was significantly larger than in the FS group (P < 0.05), while no significant difference was noted in circularity values. The complete overlap ratio in the FS group was significantly higher than that in the CCC group (P < 0.05) at each measured timepoint. Significant correlations were noted between the anterior chamber depth and the area of capsulorrhexis in the CCC group (R = 0.25, P = 0.04), but did not correlate in the FS group (P > 0.05). In patients with an anterior chamber depth >3 mm, the capsule-intraocular lens (IOL) overlap of the CCC group was less than that of the FS group at all measured timepoints after surgery (P < 0.05). Meanwhile, the IOL decentration in the CCC group was significantly greater than that of the FS group in those patients at 2 years after surgery (P < 0.05). Conclusion: In high myopic patients with cataracts, with anterior chamber depth more than 3 mm, femtosecond laser capsulotomy can achieve better capsulorrhexis sizing and centering. Due to more precise capsulotomy and a better capsule-IOL overlap in the FS group, femtosecond laser capsulotomy resulted in better long-term centration of the IOL.
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发表时间: 2020-04-27
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