COVID-19 vaccines: Keeping pace with SARS-CoV-2 variants.

COVID-19 vaccines: Keeping pace with SARS-CoV-2 variants.
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DOI:
10.1016/j.cell.2021.09.010
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发表时间:
2021-09-30
期刊:
影响因子:
64.5
通讯作者:
Openshaw P
Openshaw P
中科院分区:
生物学1区
文献类型:
--
作者:
Cevik M;Grubaugh ND;Iwasaki A;Openshaw P

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随着SARS-CoV-2大流行的演变,新的变体不断出现。一些具有高度传染性的变异,如德尔塔病毒,也引起了人们对现有疫苗有效性的担忧。了解保护的免疫学相关性以及实验室结果如何与临床效果相对应,对于制定未来的疫苗接种策略至关重要。随着SARS-CoV-2疫情的演变,新的变体不断出现。一些具有高度传染性的变异,如德尔塔病毒,也引起了人们对现有疫苗有效性的担忧。了解保护的免疫学相关性以及实验室结果如何与临床效果相对应,对于制定未来的疫苗接种策略至关重要。
As the SARS-CoV-2 pandemic evolves, new variants continue to emerge. Some highly transmissible variants, such as Delta, also raised concerns about the effectiveness provided by current vaccines. Understanding immunological correlates of protection and how laboratory findings correspond to clinical effectiveness is imperative to shape future vaccination strategies. As the SARS-CoV-2 epidemic evolves, new variants continue to emerge. Some highly transmissible variants, such as Delta, also raised concerns about the effectiveness provided by current vaccines. Understanding immunological correlates of protection and how laboratory findings correspond to clinical effectiveness is imperative to shape future vaccination strategies.
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