Risk factors for mortality from acute lower respiratory infections (ALRI) in children under five years of age in low and middle-income countries: a systematic review and meta-analysis of observational studies.
Risk factors for mortality from acute lower respiratory infections (ALRI) in children under five years of age in low and middle-income countries: a systematic review and meta-analysis of observational studies.
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低收入和中等收入国家五岁儿童急性下呼吸道感染（ALRI）死亡的危险因素：对观察性研究的系统审查和荟萃分析。
DOI：
10.1371/journal.pone.0116380
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发表时间：
2015
期刊：
影响因子：
3.7
通讯作者：
Lazzerini M
中科院分区：
文献类型：
--
作者：
Sonego M;Pellegrin MC;Becker G;Lazzerini M
评估低收入和中等收入国家儿童急性下呼吸道感染（ALRI）死亡的风险因素。系统回顾和荟萃分析.报告低收入和中等收入国家5岁以下儿童ALRI死亡风险因素的观察性研究。Medline、Embase、Global Health Library、Lilacs和Web of Science至2014年1月的预后质量研究工具，对评估偏倚风险进行了微小调整;漏斗图和Egger检验用于评估发表偏倚。在检索到的10655篇论文中，来自39个国家的77项研究（198359名儿童）符合纳入标准。与ALRI死亡率更密切相关的宿主和疾病特征为：根据WHO定义诊断为极重度肺炎（比值比9.42，95%置信区间6.37 <$13.92）;年龄小于2个月（5.22，1.70 <$16.03）;卡氏肺孢子虫的诊断（4.79，2.67 <$8.61）、慢性基础疾病（4.76，3.27 <$6.93）、艾滋病毒/艾滋病（4.68，3.72 <$5.90）和严重营养不良（OR 4.27，3.47 <$5.25）。与ALRI死亡率增加显著相关的社会经济和环境因素包括：（1.84、1.03至3.31）;母亲受教育程度低（1.43，1.13 <$1.82）;社会经济地位低（1.62，1.32 <$2.00）;二手烟暴露（1.52，1.20至1.93）;室内空气污染（3.02，2.11 <$4.31）。免疫接种（0.46，0.36 <$0.58）和良好的产前实践（0.50，0.31 <$0.81）与死亡几率降低相关。宿主和疾病特征以及社会经济和环境决定因素影响儿童ALRI死亡风险。在降低低收入和中等收入国家儿童ALRI死亡率的战略中，应考虑采取干预措施，改变贫困、缺乏女性教育和恶劣的环境条件等潜在风险因素，同时预防和治疗慢性病。收入。
To evaluate risk factors for death from acute lower respiratory infections (ALRI) in children in low- and middle-income countries. Systematic review and meta-analysis. Observational studies reporting on risk factors for death from ALRI in children below five years in low- and middle income countries. Medline, Embase, Global Health Library, Lilacs, and Web of Science to January 2014 Quality In Prognosis Studies tool with minor adaptations to assess the risk of bias; funnel plots and Egger's test to evaluate publication bias. Out of 10655 papers retrieved, 77 studies from 39 countries (198359 children) met the inclusion criteria. Host and disease characteristics more strongly associated with ALRI mortality were: diagnosis of very severe pneumonia as per WHO definition (odds ratio 9.42, 95% confidence interval 6.37‒13.92); age below two months (5.22, 1.70‒16.03); diagnosis of Pneumocystis Carinii (4.79, 2.67 ‒ 8.61), chronic underlying diseases (4.76, 3.27‒ 6.93); HIV/AIDS (4.68, 3.72‒5.90); and severe malnutrition (OR 4.27, 3.47‒5.25). Socio-economic and environmental factors significantly associated with increased odds of death from ALRI were: young maternal age (1.84, 1.03‒3.31); low maternal education (1.43, 1.13‒1.82); low socio-economic status (1.62, 1.32‒2.00); second-hand smoke exposure (1.52, 1.20 to 1.93); indoor air pollution (3.02, 2.11‒4.31). Immunisation (0.46, 0.36‒0.58) and good antenatal practices (0.50, 0.31‒0.81) were associated with decreased odds of death. Host and disease characteristics as well as socio-economic and environmental determinants affect the risk of death from ALRI in children. Together with the prevention and treatment of chronic diseases, interventions to modify underlying risk factors such as poverty, lack of female education, and poor environmental conditions, should be considered among the strategies to reduce ALRI mortality in children in low- and middle-income countries.
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控制儿童生存的家庭空气污染：干预影响的估计。
影响因子：
4.5
作者：
Bruce NG;Dherani MK;Das JK;Balakrishnan K;Adair-Rohani H;Bhutta ZA;Pope D
通讯作者：
Pope D
影响因子：
168.9
作者：
Liu, Li;Johnson, Hope L.;Black, Robert E.
通讯作者：
Black, Robert E.
DOI：
10.2471/blt.07.044529
发表时间：
2008-05-01
期刊：
Bulletin of the World Health Organization: International Journal of Public Health
影响因子：
--
作者：
Dherani, Mukesh;Pope, Daniel;Bruce, Nigel
通讯作者：
Bruce, Nigel
影响因子：
168.9
作者：
Gakidou, Emmanuela;Cowling, Krycia;Murray, Christopher J. L.
通讯作者：
Murray, Christopher J. L.
DOI：
10.1016/0197-2456(86)90046-2
发表时间：
1986-09-01
期刊：
CONTROLLED CLINICAL TRIALS
影响因子：
--
作者：
DERSIMONIAN, R;LAIRD, N
通讯作者：
LAIRD, N