Doppler optical microangiography improves the quantification of local fluid flow and shear stress within 3-D porous constructs.

Doppler optical microangiography improves the quantification of local fluid flow and shear stress within 3-D porous constructs.
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多普勒光学微血管造影改善了 3D 多孔结构内局部流体流动和剪切应力的量化。

DOI:
10.1117/1.3233590
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发表时间:
2009
影响因子:
3.5
通讯作者:
Wang,RuikangK
Wang,RuikangK
中科院分区:
医学3区
文献类型:
--
作者:
Jia,Yali;An,Lin;Wang,RuikangK

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据报道,传统的相位分辨多普勒光学相干断层扫描(DOCT)具有表征微孔支架内局部流体流动的潜力。在这项工作中,我们应用多普勒光学微血管造影术(DOMAG),一种新的成像技术相结合的光学微血管造影术(OMAG)与相分辨的方法,用于改善评估局部流体流动及其衍生参数,剪切应力和互连性,在高度散射的多孔结构。与DOCT相比,我们证明了DOMAG在功能性组织工程原位支架内定量流动相关特性方面的显着改善。
Traditional phase-resolved Doppler optical coherence tomography (DOCT) has been reported to have potential for characterizing local fluid flow within a microporous scaffold. In this work, we apply Doppler optical microangiography (DOMAG), a new imaging technique developed by combining optical microangiography (OMAG) with a phase-resolved method, for improved assessment of local fluid flow and its derived parameters, shear stress, and interconnectivity, within highly scattering porous constructs. Compared with DOCT, we demonstrate a dramatic improvement of DOMAG in quantifying flow-related properties within scaffoldsin situfor functional tissue engineering.
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发表时间: 2009-05
影响因子: 3.5
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