Ecoepidemiology, short history and control of Chagas disease in the endemic countries and the new challenge for non-endemic countries.

Ecoepidemiology, short history and control of Chagas disease in the endemic countries and the new challenge for non-endemic countries.
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DOI:
10.1590/0074-0276140236
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发表时间:
2014-11
影响因子:
2.8
通讯作者:
Junqueira AC
Junqueira AC
中科院分区:
医学4区
文献类型:
--
作者:
Coura JR;Viñas PA;Junqueira AC

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恰加斯病在自然界中通过三个周期的交换而得以维持:野生周期、生活周期和家庭周期。野生循环,这是地方性的,已经存在了数百万年的锥蝽和野生哺乳动物之间保持。在卡洛斯·查加斯于1909年发现该疾病之前,人类感染仅在4000 - 9000年前的木乃伊中发现。随着两三个世纪前美洲开始砍伐森林,以扩大农业和畜牧业,野生哺乳动物,这一直是食物来源的锥蝽,被删除,新的食物来源开始出现在peridomestic地区:鸡舍,corpus和猪圈。一些意外的人间病例也可能在锥虫病之前发生在生活区附近。因此,锥虫逐渐进入家庭,形成了南美锥虫病的家庭循环。由于感染克氏锥虫或表现出各种临床形式的查加斯病的个人从拉丁美洲流行国家法律的和非法移徙到北美、欧洲、亚洲和大洋洲的非流行国家,特别是美利坚合众国和西班牙,查加斯病的全球化造成了一个新的流行病学、经济和社会问题。本文的主要目的是提出一个一般性的看法之间的相互作用的野生,国内和国内的循环,发展的T。该报告介绍了锥虫病中的克氏锥虫病、其防治和控制举措、美洲国家的疾病特点以及向非流行国家迁移的问题。
Chagas disease is maintained in nature through the interchange of three cycles: the wild, peridomestic and domestic cycles. The wild cycle, which is enzootic, has existed for millions of years maintained between triatomines and wild mammals. Human infection was only detected in mummies from 4,000-9,000 years ago, before the discovery of the disease by Carlos Chagas in 1909. With the beginning of deforestation in the Americas, two-three centuries ago for the expansion of agriculture and livestock rearing, wild mammals, which had been the food source for triatomines, were removed and new food sources started to appear in peridomestic areas: chicken coops, corrals and pigsties. Some accidental human cases could also have occurred prior to the triatomines in peridomestic areas. Thus, triatomines progressively penetrated households and formed the domestic cycle of Chagas disease. A new epidemiological, economic and social problem has been created through the globalisation of Chagas disease, due to legal and illegal migration of individuals infected by Trypanosoma cruzi or presenting Chagas disease in its varied clinical forms, from endemic countries in Latin America to non-endemic countries in North America, Europe, Asia and Oceania, particularly to the United States of America and Spain. The main objective of the present paper was to present a general view of the interchanges between the wild, peridomestic and domestic cycles of the disease, the development of T. cruzi among triatomine, their domiciliation and control initiatives, the characteristics of the disease in countries in the Americas and the problem of migration to non-endemic countries.
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