Human papillomavirus vaccine uptake among 18- to 26-year-old women in the United States: National Health Interview Survey, 2010.
Human papillomavirus vaccine uptake among 18- to 26-year-old women in the United States: National Health Interview Survey, 2010.
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DOI：
10.1002/cncr.27894
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发表时间：
2013-04-01
期刊：
影响因子：
6.2
通讯作者：
Berenson, Abbey B.
中科院分区：
文献类型：
--
作者：
Laz, Tabassum H.;Rahman, Mahbubur;Berenson, Abbey B.
据报道，年轻成年女性的HPV疫苗接种率非常低。我们进行这项研究是为了提供18-26岁女性HPV疫苗接种的最新情况。我们使用2010年全国健康访谈调查数据来估计HPV疫苗覆盖率及其相关因素。总体而言，22.7%的女性开始接种（≥1剂），12.7%的女性完成接种（≥3剂）。多因素Logistic回归分析显示，年龄较小、未婚、巴氏试验、流感疫苗、终生接种和HPV疫苗知晓率与接种≥1剂和≥3剂疫苗呈正相关。此外，未投保的女性不太可能接受≥1剂（比值比（OR）0.49，95%置信区间（CI）0.28-0.84），黑人（OR 0.48，95% CI 0.23-0.99）和家庭收入低于联邦贫困线100%的妇女（OR 0.40，95% CI 0.21-0.73）不太可能接受≥3次给药。此外，基于疫苗接种者，黑人完成疫苗接种的可能性低于白人（OR 0.29，95% CI 0.16-0.55）。三分之二未接种疫苗的妇女对未来的疫苗接种不感兴趣。在感兴趣的人中，超过76.4%的人倾向于免费或以较低的价格获得疫苗，而20%的人愿意支付疫苗的全部费用。八分之一的女性完成了三剂HPV疫苗。需要教育和疫苗融资计划来提高宫颈癌风险增加的低收入少数族裔妇女的接种率。
HPV vaccine uptake among young adult women has been reported to be very low. We conducted this study to provide an update on HPV vaccine uptake among 18–26 year old women. We used the National Health Interview Survey 2010 data to estimate HPV vaccine coverage and their correlates. Overall, 22.7% of women initiated (≥1 dose) and 12.7% completed the vaccine (≥3 doses). Thus, about 56% of women who initiated the vaccine completed it. Multivariate logistic regression analyses showed that younger age, unmarried status, Pap test, influenza vaccine, lifetime vaccines, and HPV vaccine awareness were positively associated with receiving ≥1 and ≥3 doses. In addition, uninsured women were less likely to receive ≥1 dose (odds ratio (OR) 0.49, 95% confidence intervals (CI) 0.28–0.84), blacks (OR 0.48, 95% CI 0.23–0.99) and women with a family income <100% of the federal poverty line (OR 0.40, 95% CI 0.21–0.73) were less likely to receive ≥3 doses. Further, based on vaccine initiators, blacks were less likely than whites to complete the vaccine (OR 0.29, 95% CI 0.16–0.55). Two-thirds of unvaccinated women were not interested in future vaccination. Among those who were interested, more than 76.4% preferred to receive it free or at a lower cost while 20% would pay the full cost of the vaccine. One in 8 women completed the 3-dose HPV vaccine. Educational and vaccine financing programs are needed to improve the uptake among low-income minority women who are at increased risk for cervical cancer.
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