Organizing principles of cortical layer 6.

Organizing principles of cortical layer 6.
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DOI:
10.3389/neuro.04.003.2010
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发表时间:
2010
影响因子:
3.5
通讯作者:
Briggs F
Briggs F
中科院分区:
医学3区
文献类型:
--
作者:
Briggs F

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哺乳动物大脑皮层最深层的神经元在形态和生理上是多样的,并且位于调节局部和其他结构中的神经元活动的战略位置。第6层神经元参与的神经回路的种类在物种和皮层区域之间存在差异。然而,即使在这种多样性中,也出现了共同的组织特征。检查不同类别的第6层神经元(每个神经元专门参与不同的回路)的解剖和生理特征,可以深入了解第6层神经元对皮质信息处理的功能贡献。
Neurons in the deepest layer of mammalian cerebral cortex are morphologically and physiological diverse and are situated in a strategic position to modulate neuronal activity locally and in other structures. The variety of neuronal circuits within which layer 6 neurons participate differs across species and cortical regions. However even amidst this diversity, common organizational features emerge. Examination of the anatomical and physiological characteristics of different classes of layer 6 neuron, each specialized to participate in distinct circuits, provides insight into the functional contributions of layer 6 neurons toward cortical information processing.
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