The QT Interval as a Noninvasive Marker of Atrial Refractoriness.
The QT Interval as a Noninvasive Marker of Atrial Refractoriness.
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DOI：
10.1111/pace.12962
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发表时间：
2016-12
期刊：
影响因子：
--
通讯作者：
Marcus GM
中科院分区：
文献类型：
--
作者：
Nguyen KT;Gladstone RA;Dukes JW;Nazer B;Vittinghoff E;Badhwar N;Vedantham V;Gerstenfeld EP;Lee BK;Lee RJ;Tseng ZH;Olgin JE;Scheinman MM;Marcus GM
Atrial refractoriness may be an important determinant of atrial fibrillation (AF) risk, but its measurement is not clinically accessible. Because the QT interval predicts incident AF and the atrium and ventricle share repolarizing ion currents, we investigated the association between an individual’s QT interval and atrial effective refractory period (AERP). In paroxysmal AF patients presenting for catheter ablation, the QT interval was measured from the surface 12-lead ECG. The AERP was defined as the longest S1-S2 coupling interval without atrial capture using a 600 ms drive cycle length. In 28 patients, there was a positive correlation between QTC and mean AERP. After multivariate adjustment, a 1 ms increase in QTC predicted a 0.70 ms increase in AERP. The QTc interval reflects the AERP, suggesting that the QTc interval may be used as a marker of atrial refractoriness relevant to assessing AF risk and mechanism-specific therapeutic strategies.
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影响因子：
5.5
作者：
Lee, Jung Myung;Lee, Hancheol;Hwang, Hye Jin
通讯作者：
Hwang, Hye Jin
影响因子：
1.9
作者：
Vanhoutte K;de Asmundis C;Francesconi A;Figysl J;Steurs G;Boussy T;Roos M;Mueller A;Massimo L;Paparella G;Van Caelenberg K;Chierchia GB;Sarkozy A;Terradellas PB;Zizi M
通讯作者：
Zizi M
DOI：
10.1111/j.1540-8167.1998.tb00137.x
发表时间：
1998-09-01
影响因子：
2.7
作者：
Satoh, T;Zipes, DP
通讯作者：
Zipes, DP
DOI：
10.1111/j.1540-8159.2005.00161.x
发表时间：
2005-07-01
影响因子：
1.8
作者：
Patton, KK;Zacks, ES;Ellinor, PT
通讯作者：
Ellinor, PT
影响因子：
5.5
作者：
Mandyam, Mala C.;Soliman, Elsayed Z.;Alonso, Alvaro;Dewland, Thomas A.;Heckbert, Susan R.;Vittinghoff, Eric;Cummings, Steven R.;Ellinor, Patrick T.;Chaitman, Bernard R.;Stocke, Karen;Applegate, William B.;Arking, Dan E.;Butler, Javed;Loehr, Laura R.;Magnani, Jared W.;Murphy, Rachel A.;Satterfield, Suzanne;Newman, Anne B.;Marcus, Gregory M.
通讯作者：
Marcus, Gregory M.