Age- and sex-related differences in the retinal capillary plexus in healthy Chinese adults.
Age- and sex-related differences in the retinal capillary plexus in healthy Chinese adults.
复制标题
中国健康成年人视网膜毛细血管丛的年龄和性别相关差异
DOI：
10.1186/s40662-022-00307-0
复制
发表时间：
2022-10-01
期刊：
影响因子：
--
通讯作者：
Cui L
中科院分区：
文献类型：
--
作者：
Su B;Zhu X;Yang K;Xiao Y;Li C;Shi K;Qu J;Lu F;Li M;Cui L
To assess age- and sex-related changes in the superficial retinal capillary plexus (SCP) and deep retinal capillary plexus (DCP) in healthy Chinese adults. In this cross-sectional study, all data were derived from the community-based Jidong Eye Cohort Study. Participants underwent optical coherence tomography angiography (OCTA) and other ocular and systemic examinations. The vessel densities of the whole measured area, parafovea, and four quadrants in the SCP and DCP were measured. We recruited 1036 eyes of 1036 healthy participants; the mean age was 40.4 ± 9.8 years, and 449 (43.3%) participants were males. The SCP and DCP vessel densities in all regions, except for temporal and nasal regions in the SCP, non-linearly decreased with age. The DCP vessel densities began to decrease at approximately 35 years of age, while the SCP vessel densities began to decrease at approximately 40 years of age. The DCP vessel densities decreased more rapidly than the SCP vessel densities at 35–50 years of age. The DCP vessel densities remained stable or slightly decreased after the age of 50 years in females, while those decreased linearly in most regions in males. The retinal vessel density decreased earlier and more rapidly in the DCP than in the SCP, and the effect of aging on the DCP vessel density was sex-dependent. Our findings suggest that age and sex should be considered when interpreting clinical quantitative OCTA data. The online version contains supplementary material available at 10.1186/s40662-022-00307-0.
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影响因子：
4.4
作者：
Deschenes, Micheline C.;Descovich, Denise;Lesk, Mark R.
通讯作者：
Lesk, Mark R.
影响因子：
4.4
作者：
Garrity, Sean T.;Iafe, Nicholas A.;Sarraf, David
通讯作者：
Sarraf, David
影响因子：
2.2
作者：
Hashmani, Nauman;Hashmani, Sharif;Baig, Natasha
通讯作者：
Baig, Natasha
影响因子：
3.9
作者：
Borrelli, Enrico;Toto, Lisa;Mastropasqua, Rodolfo
通讯作者：
Mastropasqua, Rodolfo
DOI：
10.1111/j.1395-3907.2003.00160.x
发表时间：
2003-12-01
期刊：
ACTA OPHTHALMOLOGICA SCANDINAVICA
影响因子：
--
作者：
Toker, E;Yenice, Ö;Kazokoglu, H
通讯作者：
Kazokoglu, H